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. 2022 Nov 29;10(12):3074. doi: 10.3390/biomedicines10123074

Table 1.

Some of the identified molecules and compounds with antiviral activity.

Molecule Mode of Action Ref.
chloroquine/hydroxychloroquine inhibiting glycosylation of host receptors [38]
azithromycin antibiotic/anti-inflammatory activities [39]
lopinavir/ritonavir inactivation of the viral 3CL protease [40]
ribavirin blocking RNA-dependent RNA polymerase [41]
tocilizumab inhibition of IL-6 signaling [42]
baricitinib/remdesivir blocking RNA-dependent RNA polymerase [43]
favipiravir selective inhibition of viral RNA polymerase [44]
abidol broad-spectrum antiviral compound [45]
ruxolitinib competitively blocking the ATP-binding catalytic site on Janus kinases 1 and 2 [46]
teicoplanin an antibiotic applied in the prophylaxis and therapy of bacterial infections caused by Gram-positive bacteria [47]
ivermectin inhibition of the nuclear transport of viral proteins [48]
corticosteroid immunosuppressive and anti-inflammatory activities [49]
doxycycline blocking bacterial protein synthesis via binding to the 30S ribosomal subunit [50]