. 2022 Nov 28;10(12):3061. doi: 10.3390/biomedicines10123061

Table 2.

Modules containing CYP3As identified from group 1 to 4 using weighted gene co-expression network analysis.

Group	Tissue	Gene Type	Module	Module Size	CYP3A	Number of TFs	Number of ncRNAs
Group 1	Liver	All genes	Turquoise	3103	CYP3A4, 3A5 and 3A7	161	390 lncRNAs and 5 miRNAs
Group 2	Small intestine	All genes	Turquoise	4866	CYP3A4 and 3A5	339	658 lncRNAs and 3 miRNAs
Group 2	Small intestine	All genes	Red	1437	CYP3A7	55	257 lncRNAs and 4 miRNAs
Group 3	Liver	Protein coding genes	Turquoise	3090	CYP3A5 and 3A7	223	NA
Group 3	Liver	Protein coding genes	Blue	1991	CYP3A4	109	NA
Group 4	Small intestine	Protein coding genes	Blue	4078	CYP3A4 and 3A5	358	NA
Group 4	Small intestine	Protein coding genes	Green	1809	CYP3A7	83	NA

All genes in group 1 and 2 represent the genes that meet the criteria, including protein-coding genes and ncRNAs. The numbers for group 1 and 2 are 22,304 and 25,464, respectively. Protein-coding genes in group 3 and 4 represent the genes that meet the criteria, excluding ncRNAs. The numbers for group 3 and 4 are 19,273 and 21,386, respectively. NA represents not applicable. LncRNAs: Long non-coding RNAs. MiRNAs: microRNAs.