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. 2022 Nov 30;12(12):1789. doi: 10.3390/biom12121789

Figure 5.

Figure 5

Improved Coupling Compounds: Concentration response curves of compounds #3 (DS76145530) in cardiac SR and #8 (DS39746187) in skeletal SR show a percent increase in Ca2+ uptake activity that precedes the ATPase effect indicating improved coupling efficiency between the two SERCA enzymatic activities. n = 3, ±SEM.