Figure 6.

Cognition score based on behavioral study results compared to amyloid plaque burden shows donor age-dependent differences between treated mice groups. (a) Mice receiving fecal transplants from younger donors (Old Tg-FY) had higher cognition scores that correlated with lower amyloid loading compared to Old Tg-FO mice that received transplants from age-matched donors. (b) Young Tg-FY mice showed marginal decreases in amyloid load following treatment. Young Tg-FY: Young Transgenic-Fed Young, Young Tg-Control: Young Transgenic Control, Old Tg-FY: Old Transgenic-Fed Young, Old Tg-FO: Old Transgenic-Fed Old, Old Tg-Control: Old Transgenic Control.