Correction to: Linking the gut and liver: crosstalk between regulatory T cells and mucosa-associated invariant T cells

Correction to: Hepatology International (2018) 12:305–314 10.1007/s12072-018-9882-x

In this article the legend for Fig. 2 was inadvertently mislabelled and contains the wrong information; the figure should have appeared as shown below:

Figure 2 Intrahepatic MAIT cells express the semi-invariant TCR Va7.2, C-type lectin receptor CD161 and are defined as CD3 + Vα7.2 + CD161++

They express homing chemokine receptors CCR2, CCR5, CCR6, CCR9 and CXCR6. Their transcription factors include Tbet, RORgt and PLZF and the multidrug resistance transporter ABCB1. MAIT cells possess receptors to cytokines interleukin-12 (IL-12) and interleukin-18 (IL-18). Upon activation, MAIT cells release the proinflammatory cytokines TNF⍺, INFγ, Interleukin-17 (IL-17) and de-granulate Granzymes and Perforin.

Fig. 2.

Intrahepatic MAIT cells express the semi-invariant T cell receptor Va7.2, C-type lectin receptor CD161 and are defined as CD3+ Vα7.2+ CD161++. They express homing chemokine receptors CCR2, CCR5, CCR6, CCR9 and CXCR6. Their transcription factors include Tbet, RORgt, PLZF and the multidrug resistance transporter ABCB1. MAIT cells possess receptors to the cytokines interleukin-12 (IL-12) and interleukin-18 (IL-18). The MAIT cell TCR Valpha7.2+ is restricted by microbial derived vitamin B metabolites, notably Riboflavin, which act as ligands presented by MR1, a MHC Class 1-related molecule. Upon activation, MAIT cells release the proinflammatory cytokines TNF⍺, INFγ, Interleukin-17 (IL-17) and de-granulate Granzymes and Perforin.