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. 2023 Jan 13;12(2):309. doi: 10.3390/cells12020309
CAR chimeric antigen receptor
EGFR2/HER2 human epidermal growth factor receptor 2
NK Natural Killer
ICB immune checkpoint blockade
PD-1 programmed cell death 1
CTLA-4 cytotoxic T lymphocyte-associated protein 4
Ig immunoglobulin
DNAM-1/CD226 DNAX Accessory Molecule-1
ITIM immunoreceptor tyrosine-based inhibition motif
TIGIT T-cell immunoreceptor with Ig and ITIM domains
IFN interferon
HCC hepatocellular carcinoma
TNF tumor necrosis factor
TILs tumor-infiltrating lymphocytes
Ab antibody
CML chronic myeloid leukemia
AML acute myeloid leukemia
scFv single chain variable fragment
PBMCs peripheral blood mononuclear cells
KO knockout
gRNA guide RNA
WT wild-type
mAb monoclonal antibody
IC intracellular signalling domain
E:T effector:target ratio
BLI bioluminescence