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Cellular response to HSV-2-infected guinea pigs immunized with vaccines. Guinea pigs were evaluated for their Th1 (IL-2, TNF-α, and IFN-γ) and Th2 (IL-4 and IL-10) cytokines levels in serum. The secretion of cytokines IL-2 (a), TNF-α (b), IFN-γ (c), IL-4 (d), and IL-10 (e) in serum was measured by ELISA. * p < 0.05; ** p < 0.01; ns, not statistically significant.
