. 2023 Jan 1;11(1):48. doi: 10.3390/toxics11010048

Table 2.

Effect of DIOS on GNT-induced alterations in renal function biomarkers.

Groups	BUN	SCr	KIM-1
Control	32.57 $\pm$ 2.421	0.175 $\pm$ 0.034	107.80 $\pm$ 3.794
GNT	120.40 $\pm$ 5.328 ^a	1.417 $\pm$ 0.339 ^a	332.50 $\pm$ 28.120 ^a
GNT + DIOS	61.52 $\pm$ 7.413 ^a,b	0.416 $\pm$ 0.018 ^b	164.50 $\pm$ 5.526 ^a,b
DIOS	40.67 $\pm$ 5.901 ^b,c	0.194 $\pm$ 0.020 ^b	104.50 $\pm$ 6.237 ^b,c

The values designate the mean ± SD (n = 6). a: statistically significant from the control group, b: statistically significant from the GNT group, c: statistically significant from the GNT + DIOS group, p < 0.05 determined with one-way ANOVA tailed by Tukey’s multiple comparisons test. Abbreviations: BUN, blood urea nitrogen; GNT, gentamicin; KIM-1, kidney injury molecule-1; DIOS, diosmin; SCr, serum creatinine.