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. 2023 Jan 13;28(2):803. doi: 10.3390/molecules28020803

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of SIN administration on the expression of related proteins in the PG tissue of mice with TP-induced BPH. (A) The level of DHT in serum. (B) Effect of SIN administration on the expression of related proteins in the PG tissue of mice with TP-induced BPH. Protein quantification for (C) SRD5A2, (D) PCNA, (E) Bcl-2, and (F) MMP2 versus β-tubulin. Data the means ± SEM. ^### p < 0.001 versus the control group; *** p < 0.001 versus the model group. Fina, finasteride; SIN, sinomenine hydrochloride; SRD5A2, steroid 5 alpha-reductase 2; PCNA, proliferating cell nuclear antigen; Bcl-2, B-cell lymphoma-2; MMP2, matrix metallopeptidase 2.