To the editor
The review titled “Good practices for 68Ga radiopharmaceutical production” by Nelson et al. (2022) and published in the latest issue of your journal contains important information about 68Ga radiopharmaceuticals. However, sentence of the “These 68Ga radiopharmaceuticals include agents such as [68Ga]Ga-macroaggregated albumin for myocardial perfusion evaluation…” contradicts basic nuclear medicine knowledges.
68Ga-macroaggregated albumin is stated to be a potential radiopharmaceutical in lung perfusion studies in preclinical and clinical studies (Gültekin et al. 2020; Ament et al. 2013). 68Ga-macroaggregated albumin is not used in myocardial perfusion studies. I think that this error maybe caused by inattention of the author and in the review processes, and I would like to point out that it would be useful to correct it.
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AG was responsible for writing and editing the manuscript. The author read and approved the final manuscript.
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References
- Ament SJ, Maus S, Reber H, Buchholz HG, Bausbacher N, Brochhausen C, Graf F, Miederer M, Schreckenberger M. PET lung ventilation/perfusion imaging using (68)Ga aerosol (Galligas) and (68)Ga-labeled macroaggregated albumin. Recent Results Cancer Res. 2013;194:395–423. doi: 10.1007/978-3-642-27994-2_22. [DOI] [PubMed] [Google Scholar]
- Gültekin A, Çayır M, Uğur A, Bir F, Yüksel D. Detection of pulmonary embolism with Gallium-68 Macroaggregated Albumin Perfusion PET/CT: an experimental study in rabbits. Contrast Media Mol Imaging. 2020;2020:5607951. doi: 10.1155/2020/5607951. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nelson BJB, Andersson JD, Wuest F, Spreckelmeyer S. Good practices for 68Ga radiopharmaceutical production. EJNMMI Radiopharm Chem. 2022;7(1):27. doi: 10.1186/s41181-022-00180-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
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