Reactive synovitis of the knee joint and COVID‐19 vaccination: Commentary

Dear Editor,

We would like to share ideas on the publication “Reactive synovitis of the knee joint after COVID…” by Vananoskova et al. ¹ In order to find rare and long‐term side effects, Vanaskova et al recommended looking at clinical case reports on patients who received the COVID‐19 immunization. ¹ This is the first publication to provide the findings of an ultrastructural examination of post‐vaccination synovitis, according to Vanaskova et al. ¹ Ultrastructural pathology can confirm the presence of clinical problems but cannot confirm that the pathology is related to vaccination. ² No connection has been established yet. However, it can be challenging to draw any firm conclusions about the relationship between COVID‐19 problems and adverse outcomes. Drawing conclusions is now difficult because there is frequently little information available regarding patients' health and immunological state prior to the COVID‐19 vaccine. Additionally, a coexisting medical condition could be misconstrued for just a negative vaccine reaction ³ if it manifests. Investigating the cases with pre‐vaccination data further would be fascinating. In the absence of compelling evidence, it can be challenging to evaluate whether a previously reported adverse event is indeed related to vaccination.

CONFLICT OF INTEREST

None.