Skip to main content
Wiley - PMC COVID-19 Collection logoLink to Wiley - PMC COVID-19 Collection
. 2022 Dec 22:e202200306. Online ahead of print. doi: 10.1002/jbio.202200306

The effectiveness of phototherapy for surface decontamination against SARS‐Cov‐2. A systematic review

Susyane Vieira de Oliveira 1, Filipe Danilo das Neves 2, Daniela Carvalho dos Santos 2, Mariana Bernardes Batista Monteiro 2, Maristela S Schaufelberger 2, Beatriz Nascimento Motta 2, Igor Pereira de Oliveira 2, Maria Fernanda Setúbal Destro Rodrigues 1, Adriana Lino dos Santos Franco 1, Rebeca Boltes Cecatto 1,3,
PMCID: PMC9880673  PMID: 36560919

Abstract

COVID‐19 appeared in December 2019, needing efforts of science. Besides, a range of light therapies (PDT, Ultraviolet UV, Laser) has shown scientific alternatives to conventional decontamination therapies. METHODS: Investigating the efficacy of light‐based therapies for environment decontamination against SARS‐CoV2, a PRISMA systematic review of Phototherapies against SARS‐CoV or MERS‐CoV species discussing changes in viral RT‐PCR was done. After searching MEDLINE/PubMed, EMBASE, and LILACS we have found studies about cell cultures irradiation (18), blood components irradiation (10), N95 masks decontamination (03), inanimate surface decontamination (03), aerosols decontamination (03), hospital rooms irradiation (01) with PDT, LED, and UV therapy. The best quality results showed an effective low time and dose UV irradiation for environments and inanimate surfaces without human persons as long as the devices have safety elements dependent on the surfaces, viral charge, humidity, radiant exposure. To interpersonal contamination in humans, PDT or LED therapy seems very promising and are encouraged.

Keywords: COVID‐19, Decontamination, Photobiomodulation, Phototherapy, SARS‐CoV‐2


Articles from Journal of Biophotonics are provided here courtesy of Wiley

RESOURCES