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[Preprint]. 2023 Jan 12:2023.01.10.523481. [Version 1] doi: 10.1101/2023.01.10.523481

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Differential expression analysis of (A) tumor clusters from responders versus (B) tumor clusters from non-responders across all patients. C. Volcano plot of the differential expression analysis showing the most differentially expressed genes in responders (blue dots) and non-responders (green dots), showing up-regulation of immune genes in responders relative to the up-regulation of hepatocellular markers among non-responders. D. Pathway enrichment analysis between responders (red dots) and non-responders (blue dots) reveal activation of immune related pathways in responders tumors, while non-responders tumors have activation of proliferation and metabolic pathways.