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[Preprint]. 2023 Jan 12:2023.01.10.523481. [Version 1] doi: 10.1101/2023.01.10.523481

FIGURE 3.

FIGURE 3

Intercellular interaction analysis. A. Cancer-immune interaction analysis identified the activation of PAX5 network. B. and C. Cancer-CAF interaction analysis pointed to the activation of FOS and JUN networks. D. PAX5 is a transcription factor that regulate B cell activity and the PAX5 network identified co-localizes with the distribution of B cells as determined by the spatial distribution of B cell markers. E. FOS and JUN are transcription factors that can regulate genes involved in extracellular matrix remodeling and the networks regulated by these genes colocalize with CAF marker genes.