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[Preprint]. 2023 Jan 12:2023.01.10.523481. [Version 1] doi: 10.1101/2023.01.10.523481

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Cancer stem cells detection in hepatocellular carcinoma heterogeneous sample. A. Cancer stem cell markers are highly expressed at the immune poor tumor region of the responder sample with intrasample heterogeneity as noted by the spatial expression and the levels of expression are significantly different between the distinct tumor regions. B. Hepatocellular carcinoma samples from TCGA that expresses cancer stem cell markers are highly infiltrated by T CD4+ regulatory cells while T CD8+ cells are rare.