Effect of the INSIGHT Firstborn Parenting Intervention on Secondborn Sleep

Abstract

Background and Objectives

The INSIGHT responsive parenting (RP) intervention for first-time mothers improved firstborn infant sleep compared with controls. The goals of this analysis were to test intervention spillover effects on secondborn siblings, and examine birth order differences in sleep health during infancy.

Methods

Secondborns (n=117) of INSIGHT mothers enrolled in an observational cohort, SIBSIGHT. Sleep duration and behaviors were assessed using the Brief Infant Sleep Questionnaire at 3, 16, and 52 weeks. Generalized linear mixed models assessed differences among secondborns based on firstborn randomization, as well as differences between firstborns and secondborns at 16 and 52 weeks.

Results

RP group secondborns slept 42 minutes longer at night (95% CI: 19–64) and 53 minutes longer total (95% CI: 17–90) than secondborns of mothers from the control group. RP secondborns were more likely to self-soothe to sleep (OR=2.0, 95% CI: 1.1–3.7), and were less likely to be fed back to sleep after waking (OR=0.5, 95% CI: 0.3–0.9) than secondborns of control mothers. RP secondborns were more likely to have a bedtime ≤ 8pm at 3 (OR=2.9, 95% CI: 1.1–7.7) and 16 weeks (OR=4.7, 95% CI: 2.0–11.0). Few differences in sleep parenting practices were observed when comparing firstborns and secondborns within families. SBs slept 37 minutes longer than FBs at 16 weeks (CI:7–67, p=0.03).

Conclusions

The INSIGHT RP intervention for first-time mothers had a spillover effect to secondborns, positively impacting sleep duration and behaviors. Intervening with first-time mothers benefits not only firstborns but subsequent children as well.

Article Summary:

The INSIGHT responsive parenting intervention delivered to mothers with their firstborn infant improves secondborn infant sleep outcomes.

Introduction

Inadequate sleep during infancy is associated with adverse outcomes, including later risk for obesity.^1–4 For optimal health, it is recommended that infants age 4–12 months regularly sleep 12 to 16 hours per 24-hours, including naps.⁵ Sleep-related parenting practices, such as consistent bedtime routines and developmentally-appropriate responses to night wakings, play a key role in helping infants develop healthy sleep patterns.^6–8 Promoting an infant’s ability to self-soothe at night may reduce sleep disruptions for both infant and parent, and reduce reliance on nighttime feedings to soothe infants to sleep, which may prevent excess energy intake.⁹ Thus, interventions to promote development of good sleep habits in infancy may positively impact families in several ways.

The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) study is a parallel arm, randomized clinical trial comparing a responsive parenting (RP) intervention for primary prevention of obesity versus a safety control in firstborn infants.¹⁰ The RP intervention targeted parenting in several domains linked to obesity risk, including sleep. In addition to healthier weight outcomes,^11,12 firstborn infants in the RP intervention group had longer nighttime sleep duration than controls, and were less likely to be fed immediately before bed or back to sleep after night wakings. RP group infants were also more likely to have an 8pm or earlier bedtime and were more likely to self-soothe to sleep.¹³

Because many families have more than one child,¹⁴ we developed SIBSIGHT, an observational study of secondborn children from families participating in INSIGHT, with the goal of determining whether the RP intervention delivered with firstborns has ‘spillover’ benefits for secondborn children, as well as to examine birth order differences in obesity-related characteristics and parenting practices. We have previously demonstrated spillover effects of the RP intervention on infant BMI,¹⁵ parent feeding practices,¹⁶ and dietary intake of secondborns.¹⁷ This analysis focuses on sleep-related outcomes, with objectives to: 1) determine whether the INSIGHT RP intervention delivered to mothers with their firstborn affected sleep outcomes of secondborn infants and 2) explore similarities within sibling pairs and birth order differences in infant sleep duration and behaviors. We hypothesized that mothers who received the RP intervention would continue to use this guidance with their secondborn, resulting in longer sleep duration and more optimal sleep-related behaviors in secondborns from RP group families versus controls.

Methods

Participants

Primiparous mother-newborn dyads were recruited in January 2012-March 2014. Full details on recruitment, eligibility, randomization, and intervention have been previously described.^10,13 Briefly, eligible mothers were ≥20 years old and English-speaking, and infants were singleton, ≥37 weeks gestation and ≥2500 g at birth. Enrolled participants (n=279) were randomized to the INSIGHT RP intervention or a safety control intervention. Curricula were delivered by nurses at home visits at infant age 3–4, 16, 28, and 40 weeks and research center visits at 1 and 2 years, with additional messaging by phone at 18 and 30 months. The RP intervention included guidance on feeding, sleep, soothing/emotion regulation, and interactive play. Sleep messaging encouraged a consistent bedtime routine, an age-appropriate bedtime (7–8pm), and to allow infants the opportunity to self-soothe to sleep at bedtime. Regarding night wakings, mothers were encouraged to allow infants an opportunity to self-soothe themselves back to sleep, and to use alternative soothing strategies (e.g. offering a pacifier) rather than feeding infants who were not exhibiting signs of hunger. The control intervention was matched for intensity but focused on child safety; sleep-related messaging included sudden infant death syndrome (SIDS) prevention and crib safety. Families received up to $465 plus baby care gifts for participating in study visits and completing measures during the 3 year study.

INSIGHT-enrolled mothers from both the intervention and control groups who gave birth to a second child between June 2013 and March 2017 were invited to participate in the SIBSIGHT observational study (n=138 screened). Secondborns were eligible (n=122) if they were singleton, ≥36 weeks gestation and ≥2250 g at birth. All enrolled secondborns (n=117) participated through the primary study endpoint at 52 weeks. Nurses conducted visits at 3, 16, 28, and 52 weeks for data collection, but no intervention content was delivered.^10,16 Families received up to $250 for completing study visits and questionnaires. For both cohorts, mothers provided written consent for themselves and their children. The studies were approved by the Human Subjects Protection Office of the Penn State College of Medicine and registered at clinicaltrials.gov prior to enrollment of the first participant (NCT01167270). Participant flow for both studies is illustrated in Figure 1.

Figure 1:

Participant enrollment and completion for the INSIGHT and SIBSIGHT studies

Measures

Demographic data were collected at enrollment. Mothers reported on infant sleep environment, bedtime routine activities, sleep duration, and response to nighttime awakenings using the Brief Infant Sleep Questionnaire (BISQ).^6,18 Additional questions assessed specific behaviors recommended in the RP intervention. In INSIGHT, a short version of the BISQ was completed at infant age 2, 8, and 52 weeks, with full versions at 16 and 40 weeks. To match with secondborn data, only the 16 and 52 week firstborn data are used in the present analysis. In SIBSIGHT, a short version of the BISQ was completed at 3 weeks and the full BISQ was completed at 16 and 52 weeks. Surveys were completed electronically via REDCap¹⁹ or on paper if needed.

Analysis

Analyses were performed in SAS 9.4 (SAS Institute, Cary, NC). Statistical significance was defined as p<0.05. Among secondborns, main effects of firstborn study group and age of assessment (3, 16, and 52 weeks), and their interaction, were assessed. Categorical outcomes were analyzed using generalized linear mixed models with a spatial power covariance structure to account for repeated measures within subjects. Continuous outcome variables were analyzed using mixed linear models with a spatial power covariance matrix. Post-hoc analyses of significant interactions were conducted by comparison of odds ratios or least-squared means.

Birth order differences were examined at 16 weeks, when the full BISQ was collected for both siblings, and on a limited number of variables at 52 weeks, given that a short version of the BISQ was used with firstborn at this time point. Only participants that completed surveys for both siblings at a given time point (n=107 families at 16 weeks and 96 families at 52 weeks) were included in analysis. Fisher’s exact test was used to determine if firstborn sleep behaviors were associated with those in secondborns (i.e., do mothers use the same sleep parenting practices with both children?), while generalized linear mixed models were used as described above to examine birth order differences in these variables (i.e., are behaviors systematically different by birth order?). Pearson correlations were used to examine similarity in sleep duration between siblings. Birth order differences in sleep duration were assessed using linear mixed models, with repeated observations nested within sibling and siblings nested within family. Main effects of time and birth order, and their interaction, were tested, while controlling for study group assignment. Study group by birth order interactions were also examined.

Results

Secondborns (n=57 from RP families and n=60 from control families) were delivered 2.5 ± 0.8 years after their firstborn siblings. Consistent with the full INSIGHT sample, mothers with an enrolled secondborn were predominantly non-Hispanic white, married, and college-educated. There were no significant study group differences in demographic or birth characteristics of secondborns (Table 1). Inclusion of demographic covariates (child sex, spacing between births, and sex constellation [i.e., whether firstborn and secondborn were same or different sex]) in analyses did not change the results, so unadjusted analyses are presented below.

Table 1.

Demographic characteristics of mothers, firstborn infants, and secondborn infants participating in the INSIGHT RCT and SIBSIGHT observational cohort

	Reponsive Parenting		Control
	Firstborn (n=57)	Secondborn (n=57)	Firstborn (n=60)	Secondborn (n=60)
Maternal characteristics
Age at delivery, y	29.8 (4.4)	32.1 (4.2)*	28.4 (4.0)	31.1 (4.1)*
Prepregnancy BMI, kg/m2	24.8 (4.7)	25.8 (5.1)*	25.3 (5.4)	26.0 (6.0)*
Gestational weight gain, kg	14.9 (5.6)	11.1 (5.5)*	14.6 (5.1)	11.3 (6.5)*
Non-Hispanic white, n (%)	52 (93)	52 (93)	57 (95)	57 (95)
College graduate, n (%)	43 (75)	43 (75)	46 (77)	46 (77)
Married, n (%)	53 (93)	55 (97)	54 (90)	56 (93)
Household income, n (%)
<$50,000	6 (11)	3 (5)	11 (18)	5 (8)
≥$50,000	51 (89)	51 (89)	46 (77)	50 (83)
Don’t know/refuse to answer/missing	0 (0)	3 (5)	3 (5)	5 (8)
Infant characteristics
Birth weight, g	3388 (424)	3431 (442)	3449 (412)	3512 (432)
Sex, female, n (%)	30 (53)	35 (61)	32 (53)	32 (53)

Values are mean (SD) or n (%).

^*Different from firstborns in same group (p<0.05).

There were no significant differences by study group.

Intervention spillover effects on secondborn sleep duration and behaviors

Secondborns from RP families had significantly longer nighttime (7pm-7am) and total 24-hour sleep duration than secondborns from control families at 3, 16, and 52 weeks (Figure 2). Nighttime sleep increased with age, while daytime (7am-7pm) and total sleep decreased with age (all p<0.001), but there were no significant study group by age interactions, suggesting that the effects of firstborn intervention group were consistent across the three time points. On average across all time points, secondborns from RP families slept 41.6 (95% CI: 18.9–64.2) minutes longer at night and 53.3 (16.8–89.8) minutes longer over 24 hours than secondborns from control families. There was no group difference at any time point in secondborn daytime sleep duration.

Figure 2.

Sleep duration in secondborn infants of mothers enrolled in INSIGHT with their firstborn. A) Nighttime (7pm-7am) sleep duration, study group p<0.001, time p<0.001, study group-by-time interaction p=0.46; B) Total (24-h) sleep duration, study group p=0.003, time p<0.001, group-by-time interaction p=0.79. Values are mean ± 95% confidence interval.

Secondborns from RP families had greater odds of being read to during their bedtime routine than control secondborns (Table 2); this was consistent across 16 and 52 weeks (OR=2.6 (1.3–5.4), p=0.01). Following intervention recommendations, RP group mothers were less likely to rock their secondborn before bed at 52 weeks (OR=0.4 (0.2–0.8), p=0.01), with no difference at 16 weeks. Though uncommon in both groups, fewer RP than control secondborns watched TV during their bedtime routine at both 16 (0 vs 4%) and 52 (2 vs 13%) weeks. There were no study group differences or group by time interactions in the percent of mothers who reported including bathing, music, or feeding in their secondborn’s bedtime routine.

Table 2.

Bedtime routines, sleep location and behaviors among secondborn infants of mothers enrolled in the INSIGHT RCT

	3 weeks		16 weeks		52 weeks		p-value
	RP (n=51)	Control (n=56)	RP (n=53)	Control (n=55)	RP (n=53)	Control (n=55)	Group	Time point	Group × time point
Bedtime routine, %
Duration >15–≤45 min	--a	--	45	41b	52c	48b	0.58	0.26	0.92
Components
Read book	--	--	32	18	74	45	0.01	<0.001	0.36
Rocking	--	--	62	55	38	62	0.27	0.19	0.01
Bath	--	--	53	45	77	73	0.49	<0.001	0.67
Music	--	--	13	15	13	22	0.37	0.35	0.35
Watch television	--	--	0	4	2	13	0.04	0.05	NA
Bottle feed/breastfeed	--	--	94	95	89	87	0.93	0.08	0.86
Fed as last activity	--	--	21	31	23c	29	0.26	0.88	0.63
Sleep Locations and Behaviors (%)
Bedtime 8PM or earlier	29	13d	55	22	65c	63b	0.008	<0.001	0.01
Sleeps in own room	16	7d	53	49	76	76	0.32	<0.001	0.42
Falls asleep swaddled	59	59	43	22	0	5	0.31	<0.001	NA
Falls asleep with pacifier	25	36	25	31	26	33	0.22	0.90	0.91
Falls asleep with white noise	29	16	38	31	40	31	0.12	0.05	0.70
Falls asleep being held	69	77	34	53	17	33	0.02	<0.001	0.60
Falls asleep alone in room, in crib (self-soothes)	22	13	49	25	68	58	0.02	<0.001	0.42
Falls asleep in ≤15 min	--	--	75	56	83	71	0.02	0.06	0.77
Night waking, %
≥ 2 per night	94e	95	40	42	21c	20b	0.90	<0.001	0.96
≥ 2 night feedings	--	--	36	38f	19c	11f	0.48	<0.001	0.30
Parenting strategies when child wakes at night
Give a few minutes to fall back asleep	41	43	53	45	55	64	0.81	0.02	0.37
Pick up and hold/rock back to sleep	25	52	26	42	21	44	<0.001	0.60	0.69
Rub/pat but do not pick up	12	13	21	20	32	20	0.51	0.046	0.51
Feed back to sleep	47	71	55	76	30	38	0.01	<0.001	0.38
Give pacifier	22	41	36	45	28	40	0.05	0.10	0.50
Change diaper	92	80	51	67	25	38	0.75	<0.001	0.02

P-values are from generalized linear mixed model. NA = interaction could not be tested due to zero count in one or more cells; RP=Responsive parenting;

^{a-- =}Item not asked at this age;

^bn=54;

^cn=52;

^dn=55;

^en=50;

^fn=53

There was a significant study group by time interaction for the odds of secondborns meeting bedtime recommendations (Table 2). Secondborns from RP families were more likely than controls to have a bedtime of 8pm or earlier at 3 (OR=2.9 (1.1–7.7), p=0.04) and 16 (OR=4.7 (2.0–11.0), p<0.001) weeks, with no difference at 52 weeks. At 3, 16, and 52 weeks, secondborns from RP group families had higher odds of self-soothing to sleep (OR=2.0 (1.1–3.7), p=0.02), and lower odds of falling asleep while being held (OR=0.5 (0.3–0.9), p=0.02). RP group mothers were also more likely than controls to report that their secondborn took 15 minutes or less to fall asleep (OR=2.2 (1.1–4.3), p=0.02). At 16 weeks, a greater percentage of RP group secondborns fell asleep while swaddled (43 vs. 22%, Chi-Sq p=0.02). There were no group differences or group by time interactions in the percentage of secondborns who fell asleep with a pacifier or while listening to white noise.

Consistent with the RP intervention recommendations, RP group mothers were less likely than control mothers to report holding/rocking (OR=0.4 (0.2–0.6), p<0.001) or feeding (OR=0.5 (0.3–0.8), p=0.01) their secondborn to sleep following a night waking (Table 2); these differences were consistent across all three time points. There was a significant group by time interaction for changing the baby’s diaper in response to night waking, but post-hoc comparisons between study groups at each time point were not statistically significant. There were no group differences or group by time interactions in the number of mothers who reported frequent night wakings and night feedings, or giving their secondborn a few minutes to fall back asleep, rubbing/patting, or giving a pacifier after waking at night (Table 2).

Birth order differences in sleep duration and behaviors

At 16 weeks, there were modest correlations between firstborn and secondborn daytime (r=0.35, p<0.001) and total 24-hour (r=0.27, p=0.005), but not nighttime (r=0.15, p=0.14) sleep duration. At 52 weeks, similar correlations were seen between siblings for nighttime (r=0.30, p=0.004), daytime (r=0.30, p=0.004), and total (r=0.35, p<0.001) sleep duration. Birth order effects on sleep duration varied between 16 and 52 weeks and nighttime vs. daytime sleep (Figure 3). For nighttime sleep, there was a significant time by birth order interaction (p=0.02) such that firstborns slept longer than secondborns at 52 weeks only. There was also a significant time by birth order interaction for daytime (p=0.04) and total sleep (p=0.002) such that secondborns slept longer than firstborns at 16 weeks only.

Figure 3.

Firstborn and secondborn sleep duration (mean ± 95% confidence interval) at A) Nighttime (7pm-7am), n=105 dyads at 16w and n=96 at 52 weeks, birth order-by-time interaction p=0.02; B) Daytime (7am-7pm), n=105 at 16w and n=94 at 52w, birth order-by-time interaction p=0.04; C) Total (24-h), n=104 at 16w and n=89 at 52w, birth order-by-time interaction p=0.001.

Similarities and differences in sleep behaviors and parenting practices between firstborns and secondborns at 16 weeks are presented in Table 3. For each question, around 60–70% of mothers reported using the same behaviors with the secondborn as they did with their firstborn. The majority of bedtime routine components did not differ by birth order; however, secondborn bedtime routines were less likely to include reading (OR=0.4, 95% CI: 0.2–0.7, p<0.001), baths (OR=0.6, (0.4–0.9), p=0.03), and watching TV (OR=0.2, (0.04–0.9), p=0.04) than those of firstborns. Compared with firstborns, secondborns were less likely to sleep in their own room (OR=0.6, (0.4–0.8), p=0.004). There were no birth order differences in meeting the ≤ 8pm bedtime recommendation, falling asleep while swaddled, with a pacifier, with white noise, while being held, or self-soothing to sleep, or in the odds of taking 15 minutes or less to fall asleep. Regarding sleep safety, most firstborns and secondborns were put to sleep in the recommended supine position, but secondborns were less likely than firstborns to have objects such as blankets, pillows, or stuffed animals in their crib (OR=0.6 (0.4–0.9), p=0.02). There was no difference by birth order in odds of frequent night wakings or feedings, or in use of any parenting strategies in response to night waking. There were also no significant birth order by study group interactions for any outcomes.

Table 3.

Sleep behaviors and parenting practices at 16 weeks among firstborn (FB) and secondborn (SB) siblings enrolled in the INSIGHT and SIBSIGHT studies (n=107 dyads

	FB	SB	Similarity within families		Birth order effect SB vs. FBa
Variables	%	%	% agreement	Fisher’s exact test p-value	OR	95% CI	p-value
Bedtime routine, %
Duration >15-≤45 minb	42	43	64	0.009	1.1	0.7–1.8	0.71
Components
Read book	45	25	64	0.01	0.4	0.2–0.7	<0.001
Rocking	63	58	73	<0.001	0.8	0.5–1.3	0.35
Bath	61	49	67	<0.001	0.6	0.4–0.9	0.03
Music	19	14	82	0.001	0.7	0.4–1.3	0.25
Watch television	9	2	89	1.00	0.2	0.0–0.9	0.04
Bottle feed/breastfeed	94	94	88	1.00	1.2	0.4–3.8	0.78
Fed as last activity	35	26	73	<0.001	0.7	0.4–1.1	0.10
Sleep location and behaviors, %
Bedtime 8PM or earlier	32	38	69	0.001	1.4	0.8–2.3	0.23
Sleeps in own room	65	51	75	<0.001	0.6	0.4–0.8	0.004
Falls asleep swaddled	28	33	69	0.006	1.3	0.7–2.1	0.39
Falls asleep with pacifier	36	27	71	0.001	0.7	0.4–1.1	0.11
Falls asleep with white noise	30	35	71	<0.001	1.2	0.8–2.0	0.35
Falls asleep being held	45	43	70	<0.001	0.9	0.6–1.4	0.72
Falls asleep alone in room, in crib (self-soothes)	46	37	71	<0.001	0.7	0.4–1.1	0.11
Falls asleep in ≤15 min	63	66	55	0.84	1.2	0.7–2.1	0.56
Night waking, %
≥ 2 per night	33	41	62	0.06	1.4	0.9–2.4	0.16
≥ 2 night feedingsc	31	37	64	0.05	1.3	0.8–2.2	0.33
Parenting strategies
Give a few minutes to fall back asleep	58	50	67	<0.001	0.7	0.5–1.1	0.13
Pick up and hold/rock back to sleep	34	34	66	0.02	1.0	0.6–1.7	1.00
Rub/pat but do not pick up	19	20	77	0.02	1.1	0.6–1.9	0.84
Feed back to sleep	65	65	70	<0.001	1.0	0.6–1.6	1.00
Give pacifier	37	40	69	<0.001	1.1	0.7–1.8	0.60
Change diaper	68	59	61	0.10	0.7	0.4–1.1	0.12
Sleep safety, %
Supine position	91	89	91	<0.001	0.8	0.4–1.5	0.53
Unapproved object in crib (e.g., blanket, pillow)d	42	29	70	<0.001	0.6	0.4–0.9	0.02

^aOR and P value from generalized linear mixed model controlling for study group;

^bn=106 dyads;

^cn=105 dyads;

^dn=103 dyads;

Discussion

Mothers who were randomized to the INSIGHT RP intervention with their firstborn reported longer infant sleep duration and more frequent use of responsive sleep parenting practices with their secondborn, compared with mothers who were randomized to the control group with their firstborn. These study group differences are similar to those we previously reported for firstborns,¹³ suggesting an intervention spillover effect on infant sleep to secondborns despite mothers receiving no additional intervention for these younger siblings. Secondborns from RP families slept significantly longer than those from control families, and differences were consistent across measurement time points during the first year. Similar to findings with firstborns,¹³ RP group mothers were more likely than control mothers to use an age-appropriate bedtime for their secondborn, to read to their second child as part of a bedtime routine, and to allow their second child to self-soothe themselves to sleep, and were less likely to feed their second child back to sleep after waking. Parallelling our previous findings on infant BMI,¹⁵ feeding,¹⁶ and diet,¹⁷ these data suggest that intervening with first-time mothers has potential to benefit not only firstborns but subsequent children as well.

Sleep health is influenced by both genetic and environmental factors. In twin studies of young children, shared environmental influences (e.g., home environment) have the greatest contribution to sleep duration and quality, explaining 55–83% of variance, with additive genetic components contributing 5–40% and non-shared environmental factors contributing 1–17%.^20–22 For the majority of sleep-related behaviors surveyed, around 70% of mothers reported concordant answers for both siblings. These data suggest that, regardless of intervention, early life sleep parenting practices are fairly consistent across firstborn and secondborn siblings, likely contributing to the importance of shared environment. Somewhat lower concordance was observed for items that may be more reflective of infant characteristics, such as time taken to fall asleep and frequent night wakings, compared to those that are parent behaviors. Biological factors and other individual differences (e.g., temperament) may contribute to variability in sleep between siblings, warranting future investigation.

Although we observed modest correlations in infant sleep duration between siblings, secondborns had longer daytime and total sleep than firstborns at 16 weeks, but shorter nighttime sleep than firstborns at 52 weeks. Consistent with our 16 week findings, a study of 4–9 week old infants found that those who were firstborns had shorter nap and 24-hour total sleep duration than subsequent-born infants, with no difference in nighttime sleep duration.²³ Other studies have found no association between maternal parity or number of siblings and sleep duration during infancy and early childhood.^3,24 We also observed some birth order differences in sleep-related parenting practices. The bedtime routines of secondborn children were less likely to include reading books and baths than those of their firstborn sibling. With the arrival of a second child, mothers experience increased time demands resulting in “resource dilution”²⁵ and less one-on-one time with each individual child,^26,27 and often need to develop new routines to establish healthy sleep patterns for both children.²⁸ Secondborns were also less likely than firstborns to watch TV as part of their bedtime routine. Some previous research has found greater use of screen media among infants and young children without siblings,^29,30 though others have found no association.^31–33 Secondborns were less likely than firstborns to sleep in their own room rather than in their parents’ room, another finding consistent with previous research.³⁴ However, as the number of children increase, parents may have fewer options for child sleep locations and room-sharing with parents may be preferable to having infants sleep in the same room as older siblings.

A strength of this study is that we were able to compare sleep behaviors in infancy among siblings within the same family. However, these families were mostly non-Hispanic white with few lower-income households, limiting the generalizability of our findings. The SIBSIGHT sample is smaller than the original INSIGHT randomized trial. A larger sample may have yielded more power to detect study group differences in secondborns. Mothers were the primary intervention target for INSIGHT, though fathers and other caregivers were encouraged to attend study visits and review materials. Future interventions may be strengthened by more directly targeting all caregivers that contribute to sleep parenting. We did not collect concurrent information on firstborn sleep at the time of secondborn data collection, limiting our ability to assess how firstborn daily routines influence secondborn sleep. Additionally, sleep outcomes were reported by mothers via questionnaire. Though sleep duration and night wakings as measured by the BISQ have been shown to correlate with actigraphic measures,¹⁸ a more objective measure of sleep, such as actigraphy, would strengthen the results.

Conclusion

In summary, this analysis demonstrates that an RP intervention, including guidance on infant sleep, delivered to first-time mothers has positive spillover effects for secondborn infant sleep. While there were some differences by birth order in sleep outcomes, mothers’ sleep parenting of their first and secondborn child was generally more alike than different, further suggesting that interventions targeting first-time parents may have sustained benefits for future children. Clinicians should help first-time parents establish consistent bedtimes, bedtime routines, and appropriate responses to night wakings early in infancy to help firstborn and subsequent children develop healthy sleep routines. Although home-delivered parenting interventions are resource intensive, intervening on first-time parents may be a cost-effective way to reach multiple children within a family. Scalability of future interventions may be improved by incorporating the INSIGHT RP guidance into existing primary care and home visiting programs or delivering via telehealth.

What’s Known on this Subject:

The INSIGHT responsive parenting intervention for first-time mothers included education on consistent bedtime routines and nighttime parenting practices that promote self-soothing. Compared with controls, the intervention was associated with improved firstborn infant sleep behaviors and sleep duration.

What This Study Adds:

Without further intervention, INSIGHT responsive parenting group families experienced a positive spillover effect on secondborn infant sleep health, such that secondborns had longer sleep duration and were more likely to self-soothe to sleep than secondborns of control group families.

Abbreviations:

BISQ

Brief Infant Sleep Questionnaire

INSIGHT

Intervention Nurses Start Infants Growing on Healthy Trajectories

REDCap

Research Electronic Data Capture

RP

responsive parenting

Data Sharing Statement:

De-identified individual participant data (including data dictionaries) will be made available, in addition to study protocols, the statistical analysis plan, and the informed consent form. The data will be made available upon reasonable request. Proposals should be submitted to Ian Paul, ipaul@psu.edu.