Skip to main content
Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2023 Feb 6;327:137–144. doi: 10.1016/j.jad.2023.02.012

The relationship between mindfulness and mental health among Chinese college students during the closed-loop management of the COVID-19 pandemic: A moderated mediation model

Jing Yuan a,, Fang Sun b, Xiaomin Zhao c, Zejun Liu d, Qing Liang e,⁎⁎
PMCID: PMC9899704  PMID: 36754090

Abstract

To prevent the spread of the COVID-19 epidemic on campus, universities in outbreak areas in China can implement closed-loop management. Objects: This study aimed to explore the relationship between mindfulness and mental health of college students under closed-loop management. Measures: 11,939 college students from a university in Changsha, China participated in the online survey during the closed-loop management period. The Chinese version of Perceived Stress Scale, the Emotion Regulation Questionnaire-Cognitive Reappraisal, the Mindful Attention Awareness Scale, the 7-item General Anxiety Disorder questionnaire, and the 9-item Patient Health Questionnaire were administered to the college students. Results: We found that mindfulness was negative association with mental health during the closed-loop management period. Perceived stress mediated the relationship between mindfulness and mental health. Cognitive reappraisal moderated the relationship between mindfulness and perceived stress. Specifically, when the level of mindfulness is the same, individuals with more cognitive reappraisal tend to experience a less perceived stress. Conclusion: The results of this study are of great significance to improve the mental health of college students during closed-loop management period.

Keywords: Closed-loop management, Mindfulness, Perceived stress, Cognitive reappraisal, Mental health, College student

1. Introduction

The first case of an unknown pneumonia in the city of Wuhan, Hubei was reported by the World Health Organization (WHO) China Country Office in December 2019. The disease has been named the coronavirus disease 2019 (COVID-19). It has since spread widely in China and even around the world. On March 11, 2020, the WHO declared the COVID-19 a global health crisis and a pandemic (WHO, 2020). Common symptoms of COVID-19 include fever, cough, sore throat, fatigue, and shortness of breath (Jamil et al., 2020). Since then, there have been 64.9 million confirmed cases of COVID-19 and 6.6 million reported deaths (WHO, 2022). Initially, most countries adopted strict quarantine measures, such as closing national borders, locking down cities, restricting private lives (Caro et al., 2022; Lemenager et al., 2021). Three years have passed since the outbreak, many countries are in various phases of relaxing quarantine requirements while continuing some social distancing measures.

Education is one of the sectors most affected by COVID-19. Nearly 1.6 billion (91.3 %) learners in 194 countries have been affected by suspending schools and universities (UNESCO, 2020). After the initial closure, most universities are back open worldwide. In China, to prevent cross-infection and the spread of the epidemic, some colleges and universities implemented closed-loop management during the local epidemic outbreak.1 That is, during closed-loop management period, students and teachers do not leave the school and outsiders do not enter the school. Although closed-loop management can effectively prevent the spread of the epidemic on university, the change of life style, temporary social distancing, and the uncertainty of the epidemic have a certain impact on the mental health of college students (Xiao et al., 2021; Yan et al., 2022).

1.1. The impact of COVID-19 and closed-loop management on the mental health of college students

A meta-analysis of college students' mental health during COVID-19 showed the prevalence of anxiety, depression, and stress was 29 %, 37 %, and 23 %, respectively, among 436,799 college students (Wang et al., 2021). College students' main concerns about COVID-19 are the impact on the economy, daily life, and the delay in their studies (Cao et al., 2020). In addition to anxiety and depression, college students can also suffer from externalization problems, attention problems and sleep problems during COVID-19 (Copeland et al., 2021; Lai et al., 2020). Besides worrying about epidemic, the social distancing brought by closed-loop management is also a source of stress (Brooks et al., 2020; Pfefferbaum and North, 2020; Tsamakis et al., 2020; Nkire et al., 2021).

Previous studies on the impact of the COVID-19 on college students' mental health have focused on the phase of the outbreak (Savage et al., 2020; Li et al., 2021a; Li et al., 2021b; Prowse et al., 2021; Lee et al., 2021), which took place in the first half of 2020. Many colleges and universities responded to the outbreak by suspending classes and offering online courses. But few studies have looked at the impact of the COVID-19 on college students' mental health when schools reopen. In particular, the effect of closed-loop management policies implemented by Chinese universities on the mental health of college students. Because of the closed loop management, students cannot enter and leave the school freely. To some extent, students' freedom is restricted. Hence, Closed-loop management puts students in a situation of relative social isolation. While not the same as social distancing and social isolation during the outbreak of COVID-19, both result in disengagement from social integration (Berkman et al., 2000). Closed-loop management makes college students unable to participate in social activities normally and reduce their contact with friends and family. Studies show people who experienced greater social connectivity disruption during COVID-19 lockdown displayed greater disruption to social processes (Bland et al., 2022), and emotional problems, such as depression, generalized anxiety disorder and acute stress (Marroquín et al., 2020).

1.2. Mindfulness and mental health

Mindfulness is defined as conscious non-judgmental attention in the present moment (Kabat-Zinn, 1994). Although levels of mindfulness can be improved through mindfulness-based training (Querstret et al., 2018), mindfulness may also be conceptualized as a psychological trait that refers to the tendency to be mindful in daily life (Brown and Ryan, 2003).

A significant body of research shows that mindfulness improves mental health (Mandal et al., 2012; Kallapiran et al., 2015; Duan, 2016; Bice et al., 2014). As a positive psychological trait, mindfulness disposition can protect individuals from psychological distress caused by social distancing and isolation during COVID-19 (Zhu et al., 2021). As an experience, after mindfulness intervention, participants reported higher mindfulness level and fewer COVID-19-related mental health problems (Weis et al., 2021; Farris et al., 2021; González-García et al., 2021). While the relationship between mindfulness and mental health has been well established, the mechanisms by which they work have not been thoroughly explored.

1.3. The mediating role of perceived stress

Perceived stress is the result of a person's appraisal of a stressor as threatening or non-threatening (S. Liu et al., 2021; Z. Liu et al., 2021). Although people may encounter the same life events, their perceived stress may be different (Cohen et al., 1983). Prolonged stress predicts poor mental health and lower quality of life (Marshall et al., 2008; Pidgeon et al., 2014; Prior et al., 2016). High levels of perceived stress increase a person's risk of anxiety and depression. This relationship was confirmed in patients, such as kidney transplant recipients, women with breast cancer, patients with post-stroke (Laures-Gore and DeFife, 2013; Atas et al., 2021; Li et al., 2021a; Li et al., 2021b), and patients with COVID-19 (Zandifar et al., 2020). During the epidemic, as for the general public higher perceived stress was also found associated with more emotional distress including depression, fear, compulsion-anxiety, neurasthenia, and hypochondria (Yan et al., 2021). In terms of the college students, researchers have observed a positive effect of perceived stress on the anxiety (Zhang et al., 2021) and depression (S. Liu et al., 2021; Z. Liu et al., 2021).

Numerous studies have shown that mindfulness is negatively associated with perceived stress (Jedel et al., 2013; Palmer and Rodger, 2009; Dehghan et al., 2020; Prakash et al., 2015). With an increase in mindfulness as a result of interventions, perceived stress tended to decrease (Cordon et al., 2009; Manotas et al., 2014; Miller et al., 2022; Snippe et al., 2017). Mindfulness practices have also been suggested as a potential intervention to reduce stress during the COVID-19 pandemic (Ho et al., 2020; Lim et al., 2021; Bossi et al., 2022; Fazia et al., 2022). Bao et al. (2015) thought people with high levels of mindfulness are more likely to perceive a better ability to regulate their emotions, which leads to faster recovery from psychological distress and thus less perceived stress.

1.4. The moderating role of cognitive reappraisal

Emotion regulation refers to the use of emotion regulation strategies to modify the emotion dynamics and the situations (Gross, 1998; Gross, 2015). It is also considered to be an individual difference characteristic that tends to be relatively stable across time and situations (Gross and John, 2003). Cognitive reappraisal is one well-studied and frequently used emotion regulation strategy (McRae and Gross, 2020). It allows people to change the underlying evaluations that lead to negative emotions (Gross, 1998; Troy et al., 2018). Reappraisal positive emotions means changing the way one thinks in order to increase positive emotions. Reappraisal negative emotions means changing the way a person thinks in order to reduce negative emotions (Nezlek and Kuppens, 2008).

Cognitive reappraisal often is an adaptive option in the face of elevated perceived stress (Shahane et al., 2019). Individuals who believed they had higher cognitive reappraisal abilities tended to report significantly lower perceived stress (Moreira et al., 2022), and vice versa. Kuhlman et al. (2021) found greater COVID-19 impact was associated with more psychiatric symptoms among youth with lower cognitive reappraisal and less use of adaptive humor. Cognitive reappraisal can be improved with intervention. Preuss et al. (2021) conducted an online intervention for parents during the pandemic and found that compared with control group, parents in cognitive reappraisal group perceived less stress.

To investigate the mechanisms between mindfulness and mental health, we conducted this cross-sectional study with a large sample size of Chinese college students during the closed-loop management of the COVID-19 pandemic. Based on literature review, we propose the following hypothesis: (1) Mindfulness would significantly improve mental health, that is, mindfulness would be a significant negative predictor of mental health; (2) Perceived stress would mediate the relationship between mindfulness and mental health; (3) Cognitive reappraisal would moderate the relationship between mindfulness and perceived stress (see Fig. 1 for a visual representation of our hypotheses).

Fig. 1.

Fig. 1

Hypotheses model of the association between personality traits and stress.

2. Methods

2.1. Participants

From November 1 to 7, 2022, 11,939 students were recruited from a university in Hunan province, China for the online questionnaires survey. The data were collected after the students went through two months of closed-loop management on university. After excluding participants with inconsistent answers or incomplete demographic questionnaire (minimal information), 11,542 valid questionnaires were obtained. Among them, 5981 were female, accounting for 51.8 %, while 5561 were male, accounting for 48.2 %. They were aged from 16 to 29, with an average age of 20.21 ± 4.46 years old. There were 176 freshmen (1.5 %), 4026 sophomores (34.90 %), 4086 juniors (35.40 %), 3254 seniors (28.2 %). The number of freshmen was very small due to the delay in entering the school according to the COVID-19 prevention and control policies. All participants gave written informed consent in accordance with the Declaration of Helsinki. This study was approved by the Ethics Committee of the second author's university.

2.2. Measures

2.2.1. Perceived stress

The perceived stress was assessed by the Chinese version of Perceived Stress Scale (CPSS), which measures the degree to which situations in one's life are appraised as stressful (Cohen et al., 1983; Yang and Huang, 2003). The CPPS is a 14-item Likert five-point scale (1, 2, 3, 4 and 5), consisting of two subscales, nervousness and loss of control. The total score from 14 to 70. The higher the score, the more obvious the perceived stress of the participants. The Cronbach α for the CPSS was 0.85 in this study.

2.2.2. Cognitive reappraisal

Emotion Regulation Questionnaire (ERQ, Gross and John, 2003; Wang et al., 2007) is a 10-item measure of two emotion regulation strategies, cognitive reappraisal (ERQ-CR) and expressive suppression (ERQ-ES). In this study, ERQ-CR was used to assess the ability of emotion regulation. The participants were instructed to rate on a 6-item Likert seven-point scale (1, 2, …7). The total score ranges from 6 to 42. Higher scores indicate more frequent use of emotion-regulating strategies. The Cronbach α for the ERQ-CR was 0.92 in this study.

2.2.3. Mindfulness

The mindfulness was measured by the Mindful Attention Awareness Scale (MAAS), which assesses individual differences in the frequency of mindful states over time (Brown and Ryan, 2003; Chen et al., 2012). MAAS is a six-point Likert scale (1, 2, …6) with 15 items. The total score ranges from 15 to 90. The level of mindfulness can be seen as a self-regulating indicator of the individual's ability to adapt to stressful events. The higher the score, the better the self-regulation ability. The Cronbach α for the MAAS was 0.96 in this study.

2.2.4. Mental health

Since anxiety and depression were the biggest concerns for researchers during the COVID-19 pandemic, we used anxiety and depression as indicators of mental health in this study.

2.2.4.1. Anxiety

The anxiety was assessed by 7-item General Anxiety Disorder (GAD-7) questionnaire (Spitzer et al., 2006; Qu and Sheng, 2015) which is a seven-item, four-point Likert scale, with options ranging from 0 (never) to 3 (nearly every day). The total score is from 0 to 21. As GAD-7 scores goes from mild to moderate to severe (total score 0–4 = minimal, 5–9 = mild, 10–14 = moderate, 15–21 = severe), there is a substantial stepwise increase in anxiety level. The Cronbach α for the GAD-7 was 0.94 in this study.

2.2.4.2. Depression

The depression was assessed by 9-item Patient Health Questionnaire (PHQ-9). The PHQ-9 is a nine-item, self-report depression module of the full PHQ (Kroenke and Spitzer, 2002; Lai et al., 2010). PHQ-9 is based on the nine diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) and is used to diagnose major depressive Disorder (MDD). Each question is scored from “0” to “3” (0, not at all; 1, several days; 2, more than half of all the days; 3, nearly every day). The total scores from 0 to 27. As PHQ-9 scores goes from mild to moderate to severe (total score 0–4 = minimal, 5–9 = mild, 10–14 = moderate, 15–19 = moderately severe, 20–27 = severe) (Saragoussi et al., 2018), there is a substantial stepwise increase in anxiety level. The Cronbach α for the PHQ-9 was 0.93 in this study.

2.3. Statistical analysis

The data were analyzed by SPSS 25.0 and Mplus 7.0. The quantitative data were expressed as mean ± standard deviation. Correlation analysis of the variables was investigated by Pearson correlation analysis. p < 0.05 means that the difference has statistical significance. Anxiety and depression, which researchers pay most attention to, are taken as manifest variables of mental health (latent variable). Path analyses were performed to test the mediating and moderating effects. The effects were estimated by applying the bootstrapping methods, which produces 95 % bias-corrected confidence intervals (CI) from 5000 resamples that determine whether the effects were significant (Hayes 2013). A significant effect occurred when the 95%CIs did not contain zero. The variables were standardized in the mediating and moderating analyses.

3. Results

3.1. Scores of participants in perceived stress, emotion regulation, mindfulness, anxiety and depression

Statistical analysis was conducted to measure scores of participants in perceived stress, emotion regulation, mindfulness, anxiety and depression. The results showed that the score in perceived stress was 37.09 ± 8.82; the score in cognitive reappraisal was 27.87 ± 6.24; the score in mindfulness was 59.19 ± 17.11; the score in anxiety was 4.19 ± 4.12; the score in depression was 4.63 ± 4.85. The scores in each dimension and of the total scale are shown in Table 1 .

Table 1.

Descriptive analysis of variables.

Minimum value Maximum value M SD
Perceived stress 14.00 70.00 37.09 8.82
Cognitive reappraisal 6.00 42.00 27.87 6.24
Mindfulness 15.00 90.00 59.19 17.11
Anxiety 0.00 21.00 4.19 4.12
Depression 0.00 27.00 4.63 4.85

3.2. The score distribution in anxiety and depression

Descriptive analysis of the total scores of GAD-7 showed that 57.8 % of the participants had minimal anxiety, 34.0 % had mild anxiety, 5.6 % had moderate anxiety, 2.6 % had severe anxiety. In term to the PHQ-9, the results showed 57.8 % of the participants had minimal depression, 30.9 % had mild depression, 7.2 % had moderate depression, 2.6 % had moderately severe depression, and 1.6 % had severe depression (see Fig. 2 .).

Fig. 2.

Fig. 2

The distribution of anxiety (A) and depression (B) scores.

3.3. Correlations among perceived stress, cognitive reappraisal, mindfulness, anxiety and depression

Correlation analysis showed that there was significant correlation among mindfulness, perceived stress, cognitive reappraisal, anxiety, and depression. The correlation coefficients are shown in Table 2 .

Table 2.

Pearson bivariate and bilateral correlation coefficient table.

1 2 3 4 5
1 Perceived stress
2 Cognitive reappraisal −0.45⁎⁎
3 Mindfulness −0.60⁎⁎ 0.33⁎⁎
4 Anxiety 0.63⁎⁎ −0.30⁎⁎ −0.67⁎⁎
5 Depression 0.61⁎⁎ −0.33⁎⁎ −0.63⁎⁎ 0.83⁎⁎
⁎⁎

p < 0.01.

3.4. Testing for mediation effects

The present study first ran a path analysis to test the hypothesized mediation model, after controlling for gender. The results (Table 3 ) showed that mindfulness negatively predicted perceived stress (β = −0.26, p < 0.001), and mental health (β = −0.03, p < 0.01). Perceived stress positively predicted mental health (β = 0.68, p < 0.001).

Table 3.

Testing the mediation effect of perceived stress on mental health via mindfulness.

Predictors Perceived stress
Mental health
Est. SE LLCI ULCI Est. SE LLCI ULCI
Gender −0.11⁎⁎⁎ 0.009 −0.124 −0.088 −0.02 0.008 −0.034 −0.003
Perceived stress 0.68⁎⁎⁎ 0.007 0.660 0.688
Mindfulness −0.26⁎⁎⁎ 0.009 −0.276 −0.240 −0.03⁎⁎ 0.010 −0.047 −0.007
Anxiety 0.92⁎⁎⁎ 0.004 0.915 0.931
Depression 0.90⁎⁎⁎ 0.004 0.889 0.905
R2 0.08⁎⁎⁎ 0.47⁎⁎⁎

N = 11,542. Est. standardized coefficients, SE standard error, LLCI lower limit of the 95 % confidence interval, ULCI upper limit of the 95 % confidence interval.

p < 0.05.

⁎⁎

p < 0.01.

⁎⁎⁎

p < 0.001.

The study then used the bootstrapping method to calculate the mediation effects. For the mediation effects from mindfulness to mental health, the results showed that perceived stress mediated the relation between mindfulness and mental health, indirect effect = −0.008, 95%CI = [−0.086, −0.073], accounting for 86.6 % of the total effect.

3.5. Testing for moderated mediation effects

A path analysis was conducted to test the moderating role of cognitive reappraisal. As presented in Table 4 , the results indicated that cognitive reappraisal moderated the link between mindfulness and perceived stress (β = −0.12, p < 0.001). Fig. 3 illustrates the results of our testing more clearly.

Table 4.

Testing the moderated mediation effect of emotion regulation on mental health.

Predictors Perceived stress
Mental health
Est. SE LLCI ULCI Est. SE LLCI ULCI
Gender −0.09⁎⁎⁎ 0.008 −0.109 −0.077 −0.02 0.008 −0.034 −0.004
Perceived stress 0.68⁎⁎⁎ 0.007 0.660 0.688
Mindfulness −0.27⁎⁎⁎ 0.009 −0.288 −0.254 −0.03⁎⁎ 0.010 −0.047 −0.007
Cognitive reappraisal 0.46⁎⁎⁎ 0.011 0.434 0.478
Int −0.12⁎⁎⁎ 0.017 −0.152 −0.087
Anxiety 0.92⁎⁎⁎ 0.004 0.915 0.931
Depression 0.90⁎⁎⁎ 0.004 0.888 0.904
R2 0.26⁎⁎⁎ 0.47⁎⁎⁎

N = 11,542. Int = Mindfulness × Emotion regulation, Est. standardized coefficients, SE standard error, LLCI lower limit of the 95 % confidence interval, ULCI upper limit of the 95 % confidence interval.

p < 0.05.

⁎⁎

p < 0.01.

⁎⁎⁎

p < 0.001.

Fig. 3.

Fig. 3

The results of mediation testing.

For clarity, this study plotted mindfulness on perceived stress, separately at high and low levels of cognitive reappraisal (1 SD below the mean and 1 SD above the mean; see Fig. 4 ). Simple slope analyses revealed the effect between mindfulness and perceived stress was negative and significant among college students with high levels of cognitive reappraisal (β simple = −2.89, p < 0.001, 95%CI = [−3.069, −2.698]), and among college students with low levels of cognitive reappraisal (β simple = −1.90, p < 0.001, 95%CI = [−2.094, −1.692]).

Fig. 4.

Fig. 4

Cognitive appraisal moderated the relationship between mindfulness and perceived stress. CR = cognitive reappraisal.

The bootstrap analyses showed that the indirect effect of mindfulness on mental health via perceived stress was moderated by cognitive appraisal. For college student with high levels of cognitive appraisal, the indirect relationship was significant (indirect effect = −0.84, SE = 0.031, 95%CI = [−0.898, −0.778]). For college student with low levels of cognitive reappraisal, the indirect association was also significant (indirect effect = −0.55, SE = 0.030, 95%CI = [−0.610, −0.491]).

4. Discussion

The current cross-sectional study explored the relationship between mindfulness and mental health during the closed-loop management of the COVID-19 pandemic in China, and the mediating effect of perceived stress on the mindfulness-mental health relationship as well as the moderating effect of cognitive reappraisal on the mindfulness-perceived stress relationship. The results showed that participants with a higher level of mindfulness reported less mental health problems, including anxiety, depression. Moreover, the mediation model indicated that mindfulness may exert influence on mental health through perceived stress. Furthermore, the relationship of mindfulness and perceived stress was moderated by cognitive reappraisal, to be specific, when the level of mindfulness is the same, individuals with more cognitive reappraisal tend to experience a less perceived stress.

The relative quarantine brought about by closed-loop management has an adverse impact on students' mental health, although closed-loop management is an effective way to prevent students on campus from being infected. Higher levels of anxiety and depression were found among college students in this study compared to surveys conducted during the COVID-19 pandemic in 2020 (Cao et al., 2020; Sun et al., 2021; Chen et al., 2020; Qi et al., 2020). The COVID-19 outbreak coincided with the Chinese New Year holiday, so college students were at home with their families during the quarantine period. As we know, social support is an important protective factor for mental health (Harandi et al., 2017; Qi et al., 2020). While during closed-loop management period, college students are isolated in the school, away from parents and friends, so anxiety and depression levels may be higher.

College students with higher mindfulness experienced less emotional distress during the closed-loop management of COVID-19 outbreak. This finding is in line with previous research (Matiz et al., 2020; Conversano et al., 2020; Zhu et al., 2021). The relationship between mindfulness and mental health is mediated by perceived stress. Stress is associated with the development of number of mental disorders, including clinical depression, anxiety, sleep problems (Bergdahl and Bergdahl, 2002; Zhang et al., 2018). Studies have shown that people who are mindful are more likely to evaluate adverse situations as less stressful and less threatening, and they are more likely to respond to stress in adaptive ways (Weinstein et al., 2009). The mindfulness stress buffering model proposed by Creswell (2015) explains the mechanism of mindfulness in protecting mental health. According to mindfulness stress buffering model, mindfulness alleviates stress appraisals and reduces reactivity to stress, and that these stress-relieving effects partially or completely explain how mindfulness improves mental health. The mindfulness stress buffering model works through two neural circuits: Mindfulness may increase the recruitment of top-down regulatory regions of prefrontal cortex, which may inhibit the reactivity of stress-processing regions (Hölzel et al., 2013; Modinos et al., 2010). At the same time, mindfulness may have direct effects on modulating the reactivity of stress-processing regions (e.g., amygdala, anterior cingulate cortex, ventromedial prefrontal cortex, hypothalamus, parabrachial pons; for a review, see Ulrich-Lai and Herman, 2009).

In this study, we also found the moderating effect of cognitive reappraisal on the relationship between mindfulness and perceived stress. Exposure to daily stressors may be associated with a wide range of negative outcomes, including decreased well-being and increased social and health problems (Richardson, 2017). However, not all people exposed to high levels of stressors experience negative outcomes. It is well established that cognitive reappraisal has a protective effect in the development of both internalizing and externalizing psychopathology (Pepping et al., 2016). For college students with high cognitive reappraisal ability, the negative correlation between mindfulness and perceived stress is stronger, while for college students with low cognitive reappraisal ability, the negative correlation between mindfulness and perceived stress is weaker. Training college students to use this skill effectively may have the potential to provide them with lifelong protection from long-term stressors such as the global COVID-19 pandemic.

Our research results can not only increase our theoretical understanding, but also have practical significance. Our research sheds light on the relationship between mindfulness and mental health and the role of perceived stress and cognitive reappraisal, which enriches the stress buffering model and provides a reference for further relevant empirical investigations. Additionally, our findings have a direct implication for promoting cognitive reappraisal training among college students (Smith et al., 2019).

These findings should be considered in the context of their limitations. First, the present study was cross-sectional and cannot determine causal relationships among mental health during closed loop management of the COVID-19 pandemic, mindfulness, perceived stress and cognitive reappraisal. Future studies should employ a longitudinal design to examine the mediating and moderating effect. Second, the data might involve subjectivity due to self-reporting by college students in this study. More objective methods should be employed in the future study. Third, we only considered the mediating effects of perceived stress, and there are other roles such as sleep disturbances that should be taken into account in future studies. Last but not least, gender differences were not considered in this study. However, researchers found that females reported the more negative impact of COVID-19 pandemic on their academics, social isolation, stress and mental health compared to males (Prowse et al., 2021). Therefore, the gender differences in stress and coping styles should be further explored in future studies.

In summary, perceived stress and cognitive reappraisal could affect the effect of the closed-loop management during COVID-19 pandemic on college students' mental health. Developing cognitive reappraisal training might be a practicable way of maintaining and improving their mental health during a public health emergency.

Funding

This research was supported by Hebei Educational Science Planning Project (Grant No. 2203204), Medical Science Foundation of Hebei Education Department, China (Grant No. 2022X04) and Advanced Talents Incubation Program of the Hebei Education Department, China (Grant No. 521100222074).

CRediT authorship contribution statement

Jing Yuan: Conceptualization, Writing – original draft, Funding acquisition. Fang Sun: Investigation, Data curation. Xiaomin Zhao: Formal analysis. Zejun Liu: Writing – review & Editing. Qing Liang: Writing – review & editing.

Conflict of interest

The authors report there are no competing interests to declare.

Acknowledgement

Thanks to Jing Lv, Yina Chen, Jiawen Han, Yuzhuo Han and Wenjing Liu for for their contributions to data input for this study.

Footnotes

1

In December 2022, with the change of China's epidemic control policy, universities no longer implement the closed-loop management policy.

Data availability statement

Data, analytical methods, and study materials in this study are available from the corresponding author upon reasonable request.

References

  1. Atas D.B., Sunbul E.A., Velioglu A., Tuglular S. The association between perceived stress with sleep quality, insomnia, anxiety and depression in kidney transplant recipients during Covid-19 pandemic. PLoS ONE. 2021;16(3) doi: 10.1371/journal.pone.0248117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bao X., Xue S., Kong F. Dispositional mindfulness and perceived stress: The role of emotional intelligence. Personal. Individ. Differ. 2015;78:48–52. [Google Scholar]
  3. Bergdahl J., Bergdahl M. Perceived stress in adults: prevalence and association of depression, anxiety and medication in a Swedish population. Stress. Health. 2002;18(5):235–241. [Google Scholar]
  4. Berkman L.F., Glass T., Brissette I., Seeman T.E. From social integration to health: durkheim in the new millennium. Soc. Sci. Med. 2000;51:843–857. doi: 10.1016/s0277-9536(00)00065-4. [DOI] [PubMed] [Google Scholar]
  5. Bice M.R., Ball J., Ramsey A.T. Relations between mindfulness and mental health outcomes: need fulfillment as a mediator. Int. J. Ment. Health Promot. 2014;16(3):191–201. [Google Scholar]
  6. Bland A.R., Roiser J.P., Mehta M.A., Sahakian B.J., Robbins T.W., Elliott R. The impact of COVID-19 social isolation on aspects of emotional and social cognition. Cognit. Emot. 2022;36(1):49–58. doi: 10.1080/02699931.2021.1892593. [DOI] [PubMed] [Google Scholar]
  7. Bossi F., Zaninotto F., D’Arcangelo S., Lattanzi N., Malizia A.P., Ricciardi E. Mindfulness-based online intervention increases well-being and decreases stress after Covid-19 lockdown. Sci. Rep. 2022;12(1):1–13. doi: 10.1038/s41598-022-10361-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Brooks S.K., Webster R.K., Smith L.E., Woodland L., Wessely S., Greenberg N., Rubin G.J. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet. 2020;395:14–20. doi: 10.1016/S0140-6736(20)30460-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Brown K.W., Ryan R.M. The benefits of being present: mindfulness and its role in psychological well-being. J. Pers. Soc. Psychol. 2003;84(2):822–848. doi: 10.1037/0022-3514.84.4.822. [DOI] [PubMed] [Google Scholar]
  10. Cao W.J., Fang Z.W., Hou G.Q., Han M., Xu X.R., Dong J.X., Zheng J.Z. The psychological impact of the COVID-19 epidemic on college students in China. Psychiatry Res. 2020;287 doi: 10.1016/j.psychres.2020.112934. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Caro J.C., Clark A.E., d'Ambrosio C., Vögele C. The impact of COVID-19 lockdown stringency on loneliness in five European countries. Soc. Sci. Med. 2022;314 doi: 10.1016/j.socscimed.2022.115492. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Chen R., Liang S., Peng Y., Li X., Chen J., Tang S., Zhao J. Mental health status and change in living rhythms among college students in China during the COVID-19 pandemic: a large-scale survey. J. Psychosom. Res. 2020;137 doi: 10.1016/j.jpsychores.2020.110219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Chen S.Y., Cui H., Zhou R.L., Jia Y.Y. Revision of mindful attention awareness scale (MAAS) Chin. J. Clin. Psych. 2012;20(2):148–151. doi: 10.16128/j.cnki.1005-3611.2012.02.024. [DOI] [Google Scholar]
  14. Cohen S., Kamarck T., Mermelstein R. A global measure of perceived stress. Journal of Health Social Behavior. 1983;24(4):385–396. [PubMed] [Google Scholar]
  15. Conversano C., Di Giuseppe M., Miccoli M., Ciacchini R., Gemignani A., Orrù G. Mindfulness, age and gender as protective factors against psychological distress during COVID-19 pandemic. Front. Psychol. 2020;11:1900. doi: 10.3389/fpsyg.2020.01900. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Cordon S.L., Brown K.W., Gibson P.R. The role of mindfulness-based stress reduction on perceived stress: preliminary evidence for the moderating role of attachment style. J. Cogn. Psychother. 2009;23(3):258–269. [Google Scholar]
  17. Copeland W.E., McGinnis E., Bai Y., Adams Z., Nardone H., Devadanam V., Hudziak J.J.… Impact of COVID-19 pandemic on college student mental health and wellness. J. Am. Acad. Child Adolesc. Psychiatry. 2021;60(1):134–141. doi: 10.1016/j.jaac.2020.08.466. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Creswell J.D. In: Handbook of Mindfulness: Theory, Research, and Practice. Brown K.W., Creswell J.D., Ryan R.M., editors. The Guilford Press; New York: 2015. Biological pathways linking mindfulness with health; pp. 1–6. [Google Scholar]
  19. Dehghan M., Jazinizade M., Malakoutikhah A., Madadimahani A., Iranmanesh M.H., Oghabian S., Zakeri M.A. Stress and quality of life of patients with cancer: the mediating role of mindfulness. J. Oncol. 2020 doi: 10.1155/2020/3289521. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Duan W. Mediation role of individual strengths in dispositional mindfulness and mental health. Personal. Individ. Differ. 2016;99:7–10. [Google Scholar]
  21. Farris S.R., Grazzi L., Holley M., Dorsett A., Xing K., Pierce C.R., Wells R.E.… Online mindfulness may target psychological distress and mental health during COVID-19. Glob. Adv. Health Med. 2021;9:1–15. doi: 10.1177/21649561211002461. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Fazia T., Bubbico F., Nova A., Riggi E., Caimi G., Calgan B., Bernardinelli L. Online short-term mindfulness-based intervention during COVID-19 quarantine in Italy: effects on wellbeing, stress, and anxiety. Frontiers in psychology. 2022:13. doi: 10.3389/fpsyg.2022.914183. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. González-García M., Álvarez J.C., Pérez E.Z., Fernandez-Carriba S., López J.G. Feasibility of a brief online mindfulness and compassion-based intervention to promote mental health among university students during the COVID-19 pandemic. Mindfulness. 2021;12(7):1685–1695. doi: 10.1007/s12671-021-01632-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Gross J.J. The emerging field of emotion regulation: an integrative review. Rev. Gen. Psychol. 1998;2(3):271–299. [Google Scholar]
  25. Gross J.J. Emotion regulation: current status and future prospects. Psychol. Inq. 2015;26(1):1–26. [Google Scholar]
  26. Gross &amp, amp, John The emerging field of emotion regulation: an integrative review. Rev. Gen. Psychol. 2003;2(3):271–299. [Google Scholar]
  27. Harandi F.T., Taghinasab M.M., Nayeri T.D. The correlation of social support with mental health: a meta-analysis. Electron. Phys. 2017;9(9):5212–5222. doi: 10.19082/5212. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Ho C.S., Chee C.Y., Ho R.C. Mental health strategies to combat the psychological impact of COVID-19 beyond paranoia and panic. Ann. Acad. Med. Singap. 2020;49(3):155–160. [PubMed] [Google Scholar]
  29. Hölzel B.K., Hoge E.A., Greve D.N., Gard T., Creswell J.D., Brown K.W., Lazar S.W.… Neural mechanisms of symptom improvements in generalized anxiety disorder following mindfulness training. NeuroImage: Clinical. 2013;2:448–458. doi: 10.1016/j.nicl.2013.03.011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Jamil S., Mark N., Carlos G., Cruz C.S.D., Gross J.E., Pasnick S. Diagnosis and management of COVID-19 disease. Am. J. Respir. Crit. Care Med. 2020;201(10):19–20. doi: 10.1164/rccm.2020C1. [DOI] [PubMed] [Google Scholar]
  31. Jedel S., Merriman P., Hoffman A., Swanson B., Fogg L.F., Keshavarzian A. Relationship of mindfulness, quality of life, and psychiatric symptoms among patients with ulcerative colitis. Mindfulness. 2013;4(4):296–300. [Google Scholar]
  32. Kabat-Zinn J. 1st ed. Hachette Books; New York: 1994. Wherever You Go, There You are: Mindfulness Meditation in Everyday Life. [Google Scholar]
  33. Kallapiran K., Koo S., Kirubakaran R., Hancock K. Effectiveness of mindfulness in improving mental health symptoms of children and adolescents: a meta-analysis. Child Adolesc. Mental Health. 2015;20(4):182–194. doi: 10.1111/camh.12113. [DOI] [PubMed] [Google Scholar]
  34. Kroenke K., Spitzer R.L. The PHQ-9: a new depression diagnostic and severity measure. Psychiatr. Ann. 2002;32:509–515. [Google Scholar]
  35. Kuhlman K.R., Straka K., Mousavi Z., Tran M.-L., Rodgers E. Predictors of adolescent resilience during the COVID-19 pandemic: cognitive reappraisal and humor. J. Adolesc. Health. 2021;69(5):729–736. doi: 10.1016/j.jadohealth.2021.07.006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Lai A.Y.K., Lee L., Wang M.P., Feng Y., Lai T.T.K., Ho L.M., Lam T.H.… Mental health impacts of the COVID-19 pandemic on international university students, related stressors, and coping strategies. Front. Psychiatry. 2020;11 doi: 10.3389/fpsyt.2020.584240. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Lai B.P., Tang A.K., Lee D.T., Yip A.S., Chung T.K. Detecting postnatal depression in Chinese men: a comparison of three instruments. Psychiatry Res. 2010;180:80–85. doi: 10.1016/j.psychres.2009.07.015. [DOI] [PubMed] [Google Scholar]
  38. Laures-Gore J.S., DeFife L.C. Perceived stress and depression in left and right hemisphere post-stroke patients. Neuropsychol. Rehabil. 2013;23(6):783–797. doi: 10.1080/09602011.2013.811087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Lee J., Solomon M., Stead T., Kwon B., Ganti L. Impact of COVID-19 on the mental health of US college students. BMC Psychol. 2021;9(1):1–10. doi: 10.1186/s40359-021-00598-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Lemenager T., Neissner M., Koopmann A., Reinhard I., Georgiadou E., Müller A., Hillemacher T.… COVID-19 lockdown restrictions and online media consumption in Germany. Int. J. Environ. Res. Public Health. 2021;18(1):14. doi: 10.3390/ijerph18010014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Li J., Gao W., Yang Q., Cao F. Perceived stress, anxiety, and depression in treatment-naïve women with breast cancer: a case-control study. Psycho-Oncology. 2021;30(2):231–239. doi: 10.1002/pon.5555. [DOI] [PubMed] [Google Scholar]
  42. Li Y., Zhao J., Ma Z., McReynolds L.S., Lin D., Chen Z., Liu X. Mental health among college students during the COVID-19 pandemic in China: a 2-wave longitudinal survey. Journal of Affective Disorders. 2021;281:597–604. doi: 10.1016/j.jad.2020.11.109. [DOI] [PubMed] [Google Scholar]
  43. Lim J., Leow Z., Ong J., Pang L.S., Lim E. Effects of web-based group mindfulness training on stress and sleep quality in Singapore during the COVID-19 pandemic: retrospective equivalence analysis. JMIR Mental Health. 2021;8(3) doi: 10.2196/21757. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Liu S., Lithopoulos A., Zhang C.Q., Garcia-Barrera M.A., Rhodes R.E. Personality and perceived stress during COVID-19 pandemic: testing the mediating role of perceived threat and efficacy. Personal. Individ. Differ. 2021;168 doi: 10.1016/j.paid.2020.110351. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. Liu Z., Liu R., Zhang Y., Zhang R., Liang L., Wang Y., Wang F. Association between perceived stress and depression among medical students during the outbreak of COVID-19: the mediating role of insomnia. Journal of Affective Disorders. 2021;292:89–94. doi: 10.1016/j.jad.2021.05.028. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Mandal S.P., Arya Y.K., Pandey R. Mental health and mindfulness: mediational role of positive and negative affect. SIS J. Proj. Psychol. Ment. Health. 2012;19(2):150–159. [Google Scholar]
  47. Manotas M., Segura C., Eraso M., Oggins J., McGovern K. Association of brief mindfulness training with reductions in perceived stress and distress in colombian health care professionals. Int. J. Stress. Manag. 2014;21(2):207–225. [Google Scholar]
  48. Marroquín B., Vine V., Morgan R. Mental health during the COVID-19 pandemic: effects of stay-at-home policies, social distancing behavior, and social resources. Psychiatry Res. 2020;2020(293) doi: 10.1016/j.psychres.2020.113419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. Marshall L.L., Allison A., Nykamp D., Lanke S. Perceived stress and quality of life among doctor of pharmacy students. Am. J. Pharm. Educ. 2008;72(6) doi: 10.5688/aj7206137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Matiz A., Fabbro F., Paschetto A., Cantone D., Paolone A.R., Crescentini C. Positive impact of mindfulness meditation on mental health of female teachers during the COVID-19 outbreak in Italy. Int. J. Environ. Res. Public Health. 2020;17(18):6450. doi: 10.3390/ijerph17186450. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. McRae K., Gross J.J. Emotion regulation. Emotion. 2020;20(1):1–9. doi: 10.1037/emo0000703. [DOI] [PubMed] [Google Scholar]
  52. Miller M.K., Finkel J.P., Marcus B.N., Burgin E., Prosek E.A., Crace R.K., Bravo A.J. Efficacy of a university offered mindfulness training on perceived stress. Journal of Counseling & Development. 2022;100(3):278–283. [Google Scholar]
  53. Modinos G., Ormel J., Aleman A. Individual differences in dispositional mindfulness and brain activity involved in reappraisal of emotion. Soc. Cogn. Affect. Neurosci. 2010;5(4):369–377. doi: 10.1093/scan/nsq006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Moreira G.J.F., Sahi R., Ninova E., Parkinson C., Silvers J.A. Performance and belief-based emotion regulation capacity and tendency: mapping links with cognitive flexibility and perceived stress. Emotion. 2022;22(4):653. doi: 10.1037/emo0000768. [DOI] [PubMed] [Google Scholar]
  55. Nezlek J.B., Kuppens P. Regulating positive and negative emotions in daily life. J. Pers. 2008;76:561–580. doi: 10.1111/j.1467-6494.2008.00496.x. [DOI] [PubMed] [Google Scholar]
  56. Nkire N., Mrklas K., Hrabok M., Gusnowski A., Vuong W., Surood S., Agyapong V.I.O. COVID-19 pandemic: demographic predictors of self-isolation or self-quarantine and impact of isolation and quarantine on perceived stress, anxiety, and depression. Frontiers in Psychiatry. 2021;12 doi: 10.3389/fpsyt.2021.553468. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Palmer A., Rodger S. Mindfulness, stress, and coping among university students. Can. J. Couns. 2009;43(3):198–212. [Google Scholar]
  58. Pepping C.A., Duvenage M., Cronin T.J., Lyons A. Adolescent mindfulness and psychopathology: the role of emotion regulation. Personal. Individ. Differ. 2016;99:302–307. [Google Scholar]
  59. Pfefferbaum B., North C.S. Mental health and the Covid-19 pandemic. N. Engl. J. Med. 2020;383:510–512. doi: 10.1056/NEJMp2008017. [DOI] [PubMed] [Google Scholar]
  60. Pidgeon A.M., McGrath S., Magya H.B., Stapleton P., Lo B.C.Y. Psychosocial moderators of perceived stress, anxiety and depression in university students: an international study. Open J. Soc. Sci. 2014;2:23–31. [Google Scholar]
  61. Prakash R.S., Hussain M.A., Schirda B. The role of emotion regulation and cognitive control in the association between mindfulness disposition and stress. Psychol. Aging. 2015;30(1):160–171. doi: 10.1037/a0038544. [DOI] [PubMed] [Google Scholar]
  62. Preuss H., Capito K., van Eickels R.L., Zemp M., Kolar D.R. Cognitive reappraisal and self-compassion as emotion regulation strategies for parents during COVID-19: an online randomized controlled trial. Internet Interv. 2021;24 doi: 10.1016/j.invent.2021.100388. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Prior A., Fenger-Grøn M., Larsen K.K., Larsen F.B., Robinson K.M., Nielsen M.G., Vestergaard, M. The association between perceived stress and mortality among people with multimorbidity: a prospective population-based cohort study. Am. J. Epidemiol. 2016;184(3):199–210. doi: 10.1093/aje/kwv324. [DOI] [PubMed] [Google Scholar]
  64. Prowse R., Sherratt F., Abizaid A., Gabrys R.L., Hellemans K.G., Patterson Z.R., McQuaid R.J. Coping with the COVID-19 pandemic: examining gender differences in stress and mental health among university students. Front. Psychiatry. 2021;12 doi: 10.3389/fpsyt.2021.650759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. Qi M., Zhou S.J., Guo Z.C., Zhang L.G., Min H.J., Li X.M., Chen J.X. The effect of social support on mental health in chinese adolescents during the outbreak of COVID-19. J. Adolesc. Health. 2020;67:514–518. doi: 10.1016/j.jadohealth.2020.07.001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Qu S., Sheng L. Diagnostic test of screening generalized anxiety disorders in general hospital psychological department with GAD-7. Chin. Ment. Health J. 2015;29(12):939–944. [Google Scholar]
  67. Querstret D., Cropley M., Fife-Schaw C. The effects of an online mindfulness intervention on perceived stress, depression and anxiety in a non-clinical sample: a randomised waitlist control trial. Mindfulness. 2018;9(6):1825–1836. doi: 10.1007/s12671-018-0925-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Richardson C.M.E. Emotion regulation in the context of daily stress: impact on daily affect. Personal. Individ. Differ. 2017;112:150–156. [Google Scholar]
  69. Saragoussi D., Christensen M.C., Hammer-Helmich L., Rive B., Touya M., Haro J.M. Long-term follow-up on health-related quality of life in major depressive disorder: a 2-year European cohort study. Neuropsychiatr. Dis. Treat. 2018;14:1339–1350. doi: 10.2147/NDT.S159276. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. Savage M.J., James R., Magistro D., Donaldson J., Healy L.C., Nevill M., Hennis P.J. Mental health and movement behaviour during the COVID-19 pandemic in UK university students: prospective cohort study. Ment. Health Phys. Act. 2020;19 [Google Scholar]
  71. Shahane A.D., Lopez R.B., Denny B.T. Implicit reappraisal as an emotional buffer: reappraisal-related neural activity moderates the relationship between inattention and perceived stress during exposure to negative stimuli. Cognitive, Affective, & Behavioral Neuroscience. 2019;19(2):355–365. doi: 10.3758/s13415-018-00676-x. [DOI] [PubMed] [Google Scholar]
  72. Smith A., Scott I., Ratnayake J., Newsham-West K., Cathro P. An intervention study: does a cognitive reappraisal technique reduce the perceived stress in fourth-year dental students in New Zealand? International Journal of Dentistry. 2019:1–6. doi: 10.1155/2019/5864591. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Snippe E., Dziak J.J., Lanza S.T., Nyklíček I., Wichers M. The shape of change in perceived stress, negative affect, and stress sensitivity during mindfulness-based stress reduction. Mindfulness. 2017;8(3):728–736. doi: 10.1007/s12671-016-0650-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Spitzer R.L., Kroenke K., Williams J.B.W., Lowe B. A brief measure for assessing generalized anxiety disorder — the GAD-7. Arch. Intern. Med. 2006;166(10):1092–1097. doi: 10.1001/archinte.166.10.1092. [DOI] [PubMed] [Google Scholar]
  75. Sun D.K., Liao C.J., Yu R.Y. College students’ resilience and mental health during the epidemic of COVID-19: the role of coping style. J. Ningbo Univ. (Educ. Sci. Ed.) 2021;43(6):114–120. [Google Scholar]
  76. Troy A.S., Brunner A., Shallcross A.J., Friedman R., Jones M.C. Cognitive reappraisal and acceptance: effects on emotion, physiology, and perceived cognitive costs. Emotion. 2018;18(1):58–74. doi: 10.1037/emo0000371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  77. Tsamakis K., Triantafyllis A.S., Tsiptsios D., Spartalis E., Mueller C., Tsamakis C., Rizos E. COVID-19 related stress exacerbates common physical and mental pathologies and affects treatment. Experimental and Therapeutic Medicine. 2020;20:159–162. doi: 10.3892/etm.2020.8671. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Ulrich-Lai Y.M., Herman J.P. Neural regulation of endocrine and autonomic stress responses. Nat. Rev. Neurosci. 2009;10(6):397–409. doi: 10.1038/nrn2647. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. UNESCO . UNESCO; 2020. UNESCO Addresses G20 Education Ministers’ Meeting.https://en.unesco.org/news/unesco-addresses-g20-education-ministersmeeting June 29. [Google Scholar]
  80. Wang L., Liu H.C., Li Z.Q., Du W. Reliability and validity of emotion regulation questionnaire Chinese revised version. China J. Health Psychol. 2007;15(6):503–505. doi: 10.13342/j.cnki.cjhp.2007.06.012. [DOI] [Google Scholar]
  81. Wang C.Y., Wen W., Zhang H.F., Ni J., Jiang J.J., Cheng Y.R., Liu W.M. Anxiety, depression, and stress prevalence among college students during the COVID-19 pandemic: A systematic review and meta-analysis. Journal of American College Health. 2021:1–8. doi: 10.1080/07448481.2021.1960849. [DOI] [PubMed] [Google Scholar]
  82. Weinstein N., Brown K.W., Ryan R.M. A multi-method examination of the effects of mindfulness on stress attribution, coping, and emotional well-being. J. Res. Pers. 2009;43(3):374–385. [Google Scholar]
  83. Weis R., Ray S.D., Cohen T.A. Mindfulness as a way to cope with COVID-19-related stress and anxiety. Couns. Psychother. Res. 2021;21(1):8–18. [Google Scholar]
  84. World Health Organization . 2020. Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV)https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov) [Google Scholar]
  85. World Health Organization . World Health Organization; 2022. WHO Coronavirus Disease (COVID-19) Dashboard – Global Situation.https://covid19.who.int July 01. [Google Scholar]
  86. Xiao H., Shu W., Li M., Li Z., Tao Z., Wu X., Hu Y. Social distancing among medical students during the 2019 coronavirus disease pandemic in China: disease awareness, anxiety disorder, depression, and behavioral activities. International Journal of Environmental Research and Public Health. 2021;17:5047. doi: 10.3390/ijerph17145047. [DOI] [PMC free article] [PubMed] [Google Scholar]
  87. Yan L.L., Gan Y.Q., Ding X., Wu J.H., Duan H.X. The relationship between perceived stress and emotional distress during the COVID-19 outbreak: effects of boredom proneness and coping style. J. Anxiety Disord. 2021;77 doi: 10.1016/j.janxdis.2020.102328. [DOI] [PMC free article] [PubMed] [Google Scholar]
  88. Yan C.M., Mao T., Li R.C., Wang J.K., Chen Y.R. Mental health and its associated factors in college students during COVID-19 confinement in campus. Chin. J. School Health. 2022;43(7):1061–1069. [Google Scholar]
  89. Yang T.Z., Huang H.T. An epidemiological study on stress among urban residents in social transition period. Chinese Journal of Epidemiology. 2003;24(9):760–764. [PubMed] [Google Scholar]
  90. Zandifar A., Badrfam R., Yazdani S., Arzaghi S.M., Rahimi F., Ghasemi S., Qorbani M. Prevalence and severity of depression, anxiety, stress and perceived stress in hospitalized patients with COVID-19. Journal of Diabetes & Metabolic Disorders. 2020;19(2):1431–1438. doi: 10.1007/s40200-020-00667-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  91. Zhang C., Liu Q., Liu H.H., Lin N.X. The impact of Chinese college Students' perceived stress on anxiety during the COVID-19 epidemic: the mediating role of irrational beliefs. Front. Psych. 2021;12 doi: 10.3389/fpsyt.2021.731874. [DOI] [PMC free article] [PubMed] [Google Scholar]
  92. Zhang Y., Peters A., Chen G. Perceived stress mediates the associations between sleep quality and symptoms of anxiety and depression among college nursing students. Int. J. Nurs. Educ. Scholarsh. 2018;15(1) doi: 10.1515/ijnes-2017-0020. [DOI] [PubMed] [Google Scholar]
  93. Zhu J.L., Schülke R., Vatansever D., Xi D., Yan J., Zhao H., Wang S.… Mindfulness practice for protecting mental health during the COVID-19 pandemic. Transl. Psychiatry. 2021;11(1):1–11. doi: 10.1038/s41398-021-01459-8. [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Data Availability Statement

Data, analytical methods, and study materials in this study are available from the corresponding author upon reasonable request.


Articles from Journal of Affective Disorders are provided here courtesy of Elsevier

RESOURCES