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. 2022 Dec 10;9(2):e12299. doi: 10.1016/j.heliyon.2022.e12299

Table 1.

Demographics and clinical characteristics between the PBB and the non-PBB group.

PBB (N = 55) non-PBB (N = 220) P-value
Female sex 34 (61.8) 112 (50.9) 0.147
Age (ys) 46.0 (32.0–52.0) 39.5 (30.0–53.0) 0.350
Smoking status
Never smoker 48 (87.3) 192 (87.3) 0.999
Ex-smoker 6 (10.9) 17 (7.7) 0.422
Current smoker 1 (1.8) 11 (5.0) 0.470
Cough duration (mon) 3.0 (1.4–8.5) 24.0 (9.0–90.0) <0.001
Productive cough 45 (81.8) 69 (32.2) <0.001
Yellow phlegm 28 (50.9) 12 (5.6) <0.001
URTI as an initial factor 37 (67.3) 94 (42.7) 0.001
Seasonality 7 (12.7) 165 (22.2) 0.120
Occupational or environmental exposure 14 (25.5) 36 (16.4) 0.118
Timing of cough
Daily cough 48 (87.3) 194 (88.2) 0.853
Nocturnal cough 22 (40.0) 80 (36.4) 0.618
Triggers
Dust 27 (49.1) 96 (43.6) 0.467
Cold air 24 (43.6) 93 (42.3) 0.855
Cooking smell 25 (45.5) 102 (46.4) 0.904
Cigarette smoke 20 (36.4) 89 (40.5) 0.579
Lying down 10 (18.2) 36 (16.4) 0.747
Talking 18 (32.7) 85 (38.6) 0.418
Concomitant symptoms
Itchy throat 33 (60.0) 130 (59.1) 0.902
Itching below the throat 14 (25.5) 53 (24.1) 0.833
Pharyngeal foreign body sensation 20 (36.4) 82 (37.3) 0.901
Throat clearing 16 (29.1) 90 (40.9) 0.107
SMIT 37 (67.3) 87 (39.5) <0.001
Postnasal dripping 16 (29.1) 49 (22.3) 0.287
Runny nose 15 (27.3) 60 (27.3) 0.999
Acid regurgitation 5 (9.1) 38 (17.3) 0.135
Heartburn 5 (9.1) 20 (9.1) 0.999
Cough severity evaluation
Cough VAS (mm) 3.0 (2.0–4.0) 3.0 (2.0–4.0) 0.236
Daytime cough scores 1.0 (1.0–2.0) 1.0 (1.0–2.0) 0.283
Night-time cough scores 50.0 (30.0–70.0) 60.0 (50.0–70.0) 0.292
Medical history
Rhinitis 9 (16.4) 52 (23.6) 0.246
Sinusitis 6 (10.9) 31 (14.1) 0.536

Continuous variables were expressed as median (inter-quartile range, IQR). Categorical variables were presented as n (%). Among 220 patients with non-PBB, cough characteristics and sputum color were recorded in 214 patients, and cough seasonality in 212 patients. PBB: protracted bacterial bronchitis; URTI: upper respiratory tract infection; SMIT: a sensation of mucus in the throat; VAS: visual analogue scale.