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. 2023 Feb 9;23:56. doi: 10.1186/s12886-023-02781-z

Correction: Epidemiology and survival outcomes of patients with primary intraocular lymphoma: a population-based analysis

Lin-feng He 1,#, Jin-di Zhang 1,#, Xin-xin Chen 1,#, Rui-li Wei 1,
PMCID: PMC9909847  PMID: 36759809

Correction: BMC Ophthalmol 22, 486 (2022)

https://doi.org/10.1186/s12886-022-02702-6

Following publication of the original article [1], the author group identified errors in Fig. 5b and c and in Tables 2, 3 and 4. Two errors were also noted in the Results and Discussion sections.

Table 2.

Demographic and clinical characteristics of patients with primary intraocular lymphoma

Variables Total <60 ≥60 P
Number of patients(%) 326 91 (27.9) 235 (72.1)
Age
 Mean (SD) 66.1 (14.2) 48.5 (10.4) 72.9 (8.6)
 Median [Min, Max] 67.5 [8,97] 52 [8,59] 72 [60-97]
Year of diagnosis 0.059
 1992-2002 76 (23.3) 18 (19.8) 58 (24.7)
 2003-2012 138 (42.3) 48 (52.7) 90 (38.3)
 2013-2018 112 (34.4) 25 (27.5) 87 (37)
Sex 0.208
 Male 129 (39.6) 41 (45.1) 88 (37.4)
 Female 197 (60.4) 50 (54.9) 147 (62.6)
Race 0.105
 White 275 (84.4) 72 (79.1) 203 (86.4)
 Othersa 51 (15.6) 19 (20.9) 32 (13.6)
Laterality 0.202
 Unilateral 274 (84) 78 (85.7) 196 (83.4)
 Bilateral 44 (13.5) 13 (14.3) 31 (13.2)
 Unknown 8 (2.5) 8 (3.4)
Primary site 0.185
 Retina 12 (3.7) 12 (5.1)
 Choroid 24 (7.4) 7 (7.7) 17 (7.2)
 Ciliary body 66 (20.2) 19 (20.9) 47 (20)
 Vitreous 224 (68.7) 65 (71.4) 159 (67.7)
Pathological type 0.003
 DLBCL 99 (30.4) 18 (19.8) 81 (34.5)
 MALT 88 (27) 37 (40.7) 51 (21.7)
 NHL, NOS 56 (17.2) 13 (14.3) 43 (18.3)
 Other/unclassified 83 (25.5) 23 (25.3) 60 (25.5)
Ann arbor stage 0.839
 I to II 209 (64.1) 58 (63.7) 151 (64.3)
 III to IV 31 (9.5) 10 (11) 21 (8.9)
 Unknown 86 (26.4) 23 (25.3) 63 (26.8)
Surgery 0.153
 No/unknown 232 (71.2) 70 (76.9) 162 (68.9)
 Performed 94 (28.8) 21 (23.1) 73 (31.1)
Radiotherapy 0.757
 No/unknown 180 (55.2) 49 (53.8) 131 (55.7)
 Performed 146 (44.8) 42 (46.2) 104 (44.3)
Chemotherapy 0.978
 No/unknown 201 (61.7) 56 (61.5) 145 (61.7)
 Performed 125 (38.3) 35 (38.5) 90 (38.3)

Othersa: Black, American Indian/AK Native, Asian/Pacific Islander, and unknown

Other/unclassifiedb: Malignant lymphoma, Mantle cell lymphoma, Burkitt lymphoma, Follicular lymphoma, Peripheral T-cell lymphoma, Anaplastic large cell lymphoma, Chronic lymphocytic leukemia/small lymphocytic lymphoma

NHL non–Hodgkin lymphoma, NOS not otherwise specified

Table 3.

The results of the log-rank test

Variables Total <60 ≥60
Age <0.001
 <60
 ≥60
Year of diagnosis 0.006 0.329 0.035
 1992-2002
 2003-2012
 2013-2018
Sex 0.757 0.4 0.794
 Male
 Female
Race 0.188 0.091 0.785
 White
 Others
Laterality 0.05 0.03 0.072
 Unilateral
 Bilateral
 Unknown
Primary site 0.002 0.946 0.018
 Retina
 Choroid
 Ciliary body
 Vitreous
Pathological type <0.001 0.347 <0.001
 DLBCL
 MALT
 NHL, NOS
 Other/unclassifiedb
Ann arbor stage 0.057 0.22 0.032
 I to II
 III to IV
 Unknown
Surgery 0.44 0.949 0.521
 No/unknown
 Performed
Radiotherapy 0.361 0.147 0.715
 No/unknown
 Performed
Chemotherapy <0.001 0.001 0.001
 No/unknown
 Performed

Table 4.

The results of the univariate and multivariate Cox regression analysis

Variables Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Age <0.001 <0.001
 <60 Ref Ref
 ≥60 3.508 (1.904-6.464) 3.146 (1.699-5.826)
Year of diagnosis 0.008 0.054
 1992-2002 Ref
 2003-2012 0.524 (0.333-0.826)
 2013-2018 0.473 (0.251-0.89)
Sex 0.758
 Male
 Female
Race 0.189
 White
 Others
Laterality 0.051 0.115
 Unilateral
 Bilateral
 Unknown
Primary site 0.004 0.15
 Retina Ref
 Choroid 0.156 (0.047-0.52)
 Ciliary body 0.286 (0.124-0.662)
 Vitreous 0.288 (0.137-0.606)
Pathological type <0.001 0.008
 DLBCL Ref Ref
 MALT 0.144 (0.065-0.322) 0.233 (0.101-0.534)
 NHL, NOS 0.587 (0.325-1.062) 0.823 (0.439-1.543)
 Other/unclassifiedb 0.59 (0.361-0.964) 0.813 (0.489-1.353)
Ann arbor stage 0.057
 I to II
 III to IV
 Unknown
Surgery 0.441
 Performed
 No/unknown
Radiotherapy 0.362
 Performed
 No/unknown
Chemotherapy <0.001 0.003
 Performed Ref Ref
 No/unknown 0.415 (0.273-0.632) 0.498 (0.316-0.785)

The correct version of the figures and tables as well as the updated Results and Discussion sections are given below.

Fig. 5b graphic file with name 12886_2023_2781_Figa_HTML.jpg

Fig. 5c graphic file with name 12886_2023_2781_Figb_HTML.jpg

Error in Results section

On page 5, the second paragraph of the first column reads:

“The whole cohort was analyzed using log-rank tests and univariate Cox proportional hazards models, which revealed that age, years of diagnosis, laterality, primary site, pathological type, and chemotherapy had an effect on DSS.”

The sentence should read:

“The whole cohort was analyzed using log-rank tests and univariate Cox proportional hazards models, which revealed that age, years of diagnosis, primary site, pathological type, and chemotherapy had an effect on DSS.”

Error in Discussion section

On page 6, the first sentence of the first paragraph currently reads:

“In line with previous studies [2] (reference 26 in the original article], this study revealed a mean age at diagnosis of 62.5 years.”

The sentence should read:

“In line with previous studies [2] (reference 26 in the original article], this study revealed a mean age at diagnosis of 66.1 years.”

The original article [1] has been corrected.

The authors apologise for these errors.

Footnotes

Lin-feng He, Jin-di Zhang and Xin-xin Chen contributed equally to this work.

References

  • 1.He L, Zhang J, Chen X, et al. Epidemiology and survival outcomes of patients with primary intraocular lymphoma: a population-based analysis. BMC Ophthalmol. 2022;22:486. doi: 10.1186/s12886-022-02702-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Mochizuki M, Singh AD. Epidemiology and clinical features of intraocular lymphoma. Ocul Immunol Infamm. 2009;17(2):69–72. doi: 10.1080/09273940902957305. [DOI] [PubMed] [Google Scholar]

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