Correction: BMC Ophthalmol 22, 486 (2022)
https://doi.org/10.1186/s12886-022-02702-6
Following publication of the original article [1], the author group identified errors in Fig. 5b and c and in Tables 2, 3 and 4. Two errors were also noted in the Results and Discussion sections.
Table 2.
Demographic and clinical characteristics of patients with primary intraocular lymphoma
| Variables | Total | <60 | ≥60 | P |
|---|---|---|---|---|
| Number of patients(%) | 326 | 91 (27.9) | 235 (72.1) | |
| Age | ||||
| Mean (SD) | 66.1 (14.2) | 48.5 (10.4) | 72.9 (8.6) | |
| Median [Min, Max] | 67.5 [8,97] | 52 [8,59] | 72 [60-97] | |
| Year of diagnosis | 0.059 | |||
| 1992-2002 | 76 (23.3) | 18 (19.8) | 58 (24.7) | |
| 2003-2012 | 138 (42.3) | 48 (52.7) | 90 (38.3) | |
| 2013-2018 | 112 (34.4) | 25 (27.5) | 87 (37) | |
| Sex | 0.208 | |||
| Male | 129 (39.6) | 41 (45.1) | 88 (37.4) | |
| Female | 197 (60.4) | 50 (54.9) | 147 (62.6) | |
| Race | 0.105 | |||
| White | 275 (84.4) | 72 (79.1) | 203 (86.4) | |
| Othersa | 51 (15.6) | 19 (20.9) | 32 (13.6) | |
| Laterality | 0.202 | |||
| Unilateral | 274 (84) | 78 (85.7) | 196 (83.4) | |
| Bilateral | 44 (13.5) | 13 (14.3) | 31 (13.2) | |
| Unknown | 8 (2.5) | 8 (3.4) | ||
| Primary site | 0.185 | |||
| Retina | 12 (3.7) | 12 (5.1) | ||
| Choroid | 24 (7.4) | 7 (7.7) | 17 (7.2) | |
| Ciliary body | 66 (20.2) | 19 (20.9) | 47 (20) | |
| Vitreous | 224 (68.7) | 65 (71.4) | 159 (67.7) | |
| Pathological type | 0.003 | |||
| DLBCL | 99 (30.4) | 18 (19.8) | 81 (34.5) | |
| MALT | 88 (27) | 37 (40.7) | 51 (21.7) | |
| NHL, NOS | 56 (17.2) | 13 (14.3) | 43 (18.3) | |
| Other/unclassified | 83 (25.5) | 23 (25.3) | 60 (25.5) | |
| Ann arbor stage | 0.839 | |||
| I to II | 209 (64.1) | 58 (63.7) | 151 (64.3) | |
| III to IV | 31 (9.5) | 10 (11) | 21 (8.9) | |
| Unknown | 86 (26.4) | 23 (25.3) | 63 (26.8) | |
| Surgery | 0.153 | |||
| No/unknown | 232 (71.2) | 70 (76.9) | 162 (68.9) | |
| Performed | 94 (28.8) | 21 (23.1) | 73 (31.1) | |
| Radiotherapy | 0.757 | |||
| No/unknown | 180 (55.2) | 49 (53.8) | 131 (55.7) | |
| Performed | 146 (44.8) | 42 (46.2) | 104 (44.3) | |
| Chemotherapy | 0.978 | |||
| No/unknown | 201 (61.7) | 56 (61.5) | 145 (61.7) | |
| Performed | 125 (38.3) | 35 (38.5) | 90 (38.3) | |
Othersa: Black, American Indian/AK Native, Asian/Pacific Islander, and unknown
Other/unclassifiedb: Malignant lymphoma, Mantle cell lymphoma, Burkitt lymphoma, Follicular lymphoma, Peripheral T-cell lymphoma, Anaplastic large cell lymphoma, Chronic lymphocytic leukemia/small lymphocytic lymphoma
NHL non–Hodgkin lymphoma, NOS not otherwise specified
Table 3.
The results of the log-rank test
| Variables | Total | <60 | ≥60 |
|---|---|---|---|
| Age | <0.001 | ||
| <60 | |||
| ≥60 | |||
| Year of diagnosis | 0.006 | 0.329 | 0.035 |
| 1992-2002 | |||
| 2003-2012 | |||
| 2013-2018 | |||
| Sex | 0.757 | 0.4 | 0.794 |
| Male | |||
| Female | |||
| Race | 0.188 | 0.091 | 0.785 |
| White | |||
| Others | |||
| Laterality | 0.05 | 0.03 | 0.072 |
| Unilateral | |||
| Bilateral | |||
| Unknown | |||
| Primary site | 0.002 | 0.946 | 0.018 |
| Retina | |||
| Choroid | |||
| Ciliary body | |||
| Vitreous | |||
| Pathological type | <0.001 | 0.347 | <0.001 |
| DLBCL | |||
| MALT | |||
| NHL, NOS | |||
| Other/unclassifiedb | |||
| Ann arbor stage | 0.057 | 0.22 | 0.032 |
| I to II | |||
| III to IV | |||
| Unknown | |||
| Surgery | 0.44 | 0.949 | 0.521 |
| No/unknown | |||
| Performed | |||
| Radiotherapy | 0.361 | 0.147 | 0.715 |
| No/unknown | |||
| Performed | |||
| Chemotherapy | <0.001 | 0.001 | 0.001 |
| No/unknown | |||
| Performed |
Table 4.
The results of the univariate and multivariate Cox regression analysis
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | <0.001 | <0.001 | ||
| <60 | Ref | Ref | ||
| ≥60 | 3.508 (1.904-6.464) | 3.146 (1.699-5.826) | ||
| Year of diagnosis | 0.008 | 0.054 | ||
| 1992-2002 | Ref | |||
| 2003-2012 | 0.524 (0.333-0.826) | |||
| 2013-2018 | 0.473 (0.251-0.89) | |||
| Sex | 0.758 | |||
| Male | ||||
| Female | ||||
| Race | 0.189 | |||
| White | ||||
| Others | ||||
| Laterality | 0.051 | 0.115 | ||
| Unilateral | ||||
| Bilateral | ||||
| Unknown | ||||
| Primary site | 0.004 | 0.15 | ||
| Retina | Ref | |||
| Choroid | 0.156 (0.047-0.52) | |||
| Ciliary body | 0.286 (0.124-0.662) | |||
| Vitreous | 0.288 (0.137-0.606) | |||
| Pathological type | <0.001 | 0.008 | ||
| DLBCL | Ref | Ref | ||
| MALT | 0.144 (0.065-0.322) | 0.233 (0.101-0.534) | ||
| NHL, NOS | 0.587 (0.325-1.062) | 0.823 (0.439-1.543) | ||
| Other/unclassifiedb | 0.59 (0.361-0.964) | 0.813 (0.489-1.353) | ||
| Ann arbor stage | 0.057 | |||
| I to II | ||||
| III to IV | ||||
| Unknown | ||||
| Surgery | 0.441 | |||
| Performed | ||||
| No/unknown | ||||
| Radiotherapy | 0.362 | |||
| Performed | ||||
| No/unknown | ||||
| Chemotherapy | <0.001 | 0.003 | ||
| Performed | Ref | Ref | ||
| No/unknown | 0.415 (0.273-0.632) | 0.498 (0.316-0.785) | ||
The correct version of the figures and tables as well as the updated Results and Discussion sections are given below.
Fig. 5b

Fig. 5c

Error in Results section
On page 5, the second paragraph of the first column reads:
“The whole cohort was analyzed using log-rank tests and univariate Cox proportional hazards models, which revealed that age, years of diagnosis, laterality, primary site, pathological type, and chemotherapy had an effect on DSS.”
The sentence should read:
“The whole cohort was analyzed using log-rank tests and univariate Cox proportional hazards models, which revealed that age, years of diagnosis, primary site, pathological type, and chemotherapy had an effect on DSS.”
Error in Discussion section
On page 6, the first sentence of the first paragraph currently reads:
“In line with previous studies [2] (reference 26 in the original article], this study revealed a mean age at diagnosis of 62.5 years.”
The sentence should read:
“In line with previous studies [2] (reference 26 in the original article], this study revealed a mean age at diagnosis of 66.1 years.”
The original article [1] has been corrected.
The authors apologise for these errors.
Footnotes
Lin-feng He, Jin-di Zhang and Xin-xin Chen contributed equally to this work.
References
- 1.He L, Zhang J, Chen X, et al. Epidemiology and survival outcomes of patients with primary intraocular lymphoma: a population-based analysis. BMC Ophthalmol. 2022;22:486. doi: 10.1186/s12886-022-02702-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Mochizuki M, Singh AD. Epidemiology and clinical features of intraocular lymphoma. Ocul Immunol Infamm. 2009;17(2):69–72. doi: 10.1080/09273940902957305. [DOI] [PubMed] [Google Scholar]
