Skip to main content
. 2022 Jul 11;164(3):469–484. doi: 10.1097/j.pain.0000000000002723

Table 3.

Overview of used placebo control interventions per therapy type.

Therapy type Total N Placebo control or sham interventions N %
Manual therapy with spinal manipulation 49 Manual, simulated manoeuvre 30 61.2
Manual, soft touch 9 18.4
Manual, technique to different area 1 2.0
Disabled device 6 12.2
Rest time-control 1 2.0
Other (therapist attention, general anaesthesia) 2 4.1
Craniosacral therapy and gentle myofascial release 22 Manual, simulated manoeuvre 2 9.1
Manual, soft touch 8 36.4
Disabled device 10 45.5
Other (low-strength static magnets, active joint movement) 2 9.1
Other manual therapy 63 Manual, simulated manoeuvre 21 33.3
Manual, soft touch 19 30.2
Manual, technique to different area 1 1.6
Manual, simulated manoeuvre and to different area 1 1.6
Disabled device 16 25.4
Other (time-attention control, therapist attention, active joint movement, 2x low-pressure algometry) 5 7.9
Rehabilitation or physiotherapy 22 Exercise, nonspecific 8 36.4
Exercise, key components altered 1 4.5
Disabled device 5 22.7
Manual, simulated manoeuvre 1 4.5
Manual, soft touch 1 4.5
Educational attention control 5 22.7
Other (nonspecific visualisation, rest + therapist attention) 2 9.1
Cognitive-behavioural and other psychotherapy 27 Multicomponent therapist interaction 11 40.7
Educational attention control 7 25.9
Cognitive task, nonspecific 2 7.4
Writing attention control 2 7.4
Other (relaxing music, nonspecific visualisation, open-label saline injection, nonhypnotic relaxation suggestions and white noise, nonspecific video and sound) 5 18.5
Spiritual, energetic, or esoteric healing 8 Simulated hands-off manoeuvre (actor) 7 87.5
Simulated hands-on manoeuvre (actor) 1 12.5
Self-management 5 Rest time control 2 40.0
Educational attention control 1 20.0
Web site, nonspecific 1 20.0
Other (white noise) 1 20.0
Other 2 Other (white noise, headphones without sound) 2 100.0

N = 198.