Cell Biology Retraction for “Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells,” by Jing Li, Alfredo Csibi, Sun Yang, Gregory R. Hoffman, Chenggang Li, Erik Zhang, Jane J. Yu, and John Blenis, which was first published December 18, 2014; 10.1073/pnas.1417015112 (Proc. Natl. Acad. Sci. U.S.A. 112, E21–E29).
The undersigned authors note, “We are retracting this article due to the following errors in the preparation of several of the published figures. The same data appear to be presented in the +Rapa/+17AAG/48h panel of Fig. 2A and in the BPTES + 17AAG + NAC (72h) panel of Fig. 5D. In the p62 panels of Fig. 3D and SI Appendix, Fig. S2, the same data appear to be presented in lanes 1 and 5 of Fig. 3D and lanes 1 and 2 of SI Appendix, Fig. S2; in lane 6 of Fig. 3D and lane 3 of SI Appendix, Fig. S2; and in lane 7 of Fig. 3D and lane 4 of SI Appendix, Fig. S2. The same data appear to be presented in lanes 1 to 12 of the α-Tubulin panel of SI Appendix, Fig. S3B and the full GAPDH panel of SI Appendix, Fig. S4A. In the Cleaved PARP of SI Appendix, Fig. S4A, the same data appear to be presented in lanes 4 and 12; and in lanes 7 and 8. In SI Appendix, Fig. S5A, the same data appear to be presented in lanes 8 and 11 of the Cleaved PARP panel. Also in SI Appendix, Fig. S5A, the same data appear to be presented in lanes 5 and 8 of the P-elF2α panel. We sincerely regret any inconvenience to the scientific community this may have caused.”
Jing Li, Gregory R. Hoffman, Jane J. Yu, and John Blenis