表 1. Genes expression of induction groups compared with that of control group (n=3).
诱导组与对照组基因表达的比较(n=3)
| 基因 | 24 h | 48 h | 72 h | 基因 | 24 h | 48 h | 72 h | |||||||||||
| 变化 | 评价 | 变化 | 评价 | 变化 | 评价 | 变化 | 评价 | 变化 | 评价 | 变化 | 评价 | |||||||
| ↑表示上调基因,↓表示下调基因,空白为无变化基因。OK 表示结果重复性优,A 表示结果重复性良好,B 表示结果重复性一般,C 表示结果重复性差 | ||||||||||||||||||
| Adrb1 | ↓ | OK | B | ↓ | OK | Kcna5 | B | OK | ↑ | OK | ||||||||
| Ahr | ↑ | OK | ↓ | A | ↑ | OK | Krtap14 | C | C | OK | ||||||||
| Amd1 | ↑ | OK | ↑ | OK | OK | Ldha | ↑ | OK | OK | OK | ||||||||
| Areg | ↑ | OK | ↑ | OK | ↑ | OK | Maf | OK | OK | ↓ | OK | |||||||
| Atf3 | ↑ | OK | ↑ | OK | ↑ | OK | Mif | ↑ | OK | ↑ | OK | OK | ||||||
| Bcl2 | ↑ | OK | ↑ | OK | ↑ | OK | Ncam1 | ↑ | OK | ↑ | OK | ↑ | OK | |||||
| Bdnf | ↑ | OK | ↑ | OK | ↑ | OK | Nf1 | OK | ↑ | OK | OK | |||||||
| Brca1 | OK | OK | OK | Nos2 | ↓ | A | ↓ | OK | ↓ | A | ||||||||
| Calb1 | ↓ | OK | B | OK | Npy | ↓ | OK | ↓ | OK | ↓ | OK | |||||||
| Calb2 | ↓ | OK | ↓ | OK | ↓ | OK | Pck2 | ↑ | OK | ↑ | OK | ↑ | OK | |||||
| Calcrl | ↑ | OK | ↑ | OK | ↑ | OK | Pcna | ↑ | OK | ↑ | OK | OK | ||||||
| Calm1 | OK | OK | OK | Penk | ↓ | A | A | ↑ | OK | |||||||||
| Calr | OK | ↑ | OK | OK | Per1 | OK | ↑ | OK | OK | |||||||||
| Ccna1 | ↓ | OK | B | ↓ | OK | Plat | OK | OK | OK | |||||||||
| Ccnd1 | OK | OK | OK | Pln | ↓ | OK | OK | ↓ | A | |||||||||
| Cdk5 | OK | OK | OK | Pmaip1 | ↑ | OK | ↑ | OK | OK | |||||||||
| Cdkn2b | B | B | B | Pou1f1 | OK | ↑ | OK | OK | ||||||||||
| Cga | ↓ | OK | ↓ | OK | ↑ | OK | Pou2af1 | ↓ | OK | ↓ | OK | ↓ | OK | |||||
| Chga | ↓ | OK | ↓ | OK | ↑ | A | Ppp1r15a | ↑ | OK | ↑ | OK | ↑ | OK | |||||
| Cnn1 | ↓ | OK | B | B | Ppp2ca | ↑ | OK | ↑ | OK | ↑ | OK | |||||||
| Creb1 | ↑ | OK | ↑ | OK | ↑ | OK | Prkar1a | ↑ | OK | ↑ | OK | OK | ||||||
| Crem | OK | OK | OK | Prl | ↓ | OK | ↓ | OK | ↓ | OK | ||||||||
| Crh | B | B | B | Ptgs2 | ↑ | OK | ↑ | OK | ↑ | OK | ||||||||
| Cyr61 | ↑ | OK | ↑ | OK | ↑ | OK | Rb1 | OK | ↑ | OK | OK | |||||||
| Ddit3 | ↑ | OK | ↑ | OK | ↑ | OK | S100a8 | ↓ | OK | ↓ | OK | ↓ | OK | |||||
| Dusp1 | ↑ | OK | ↑ | OK | ↑ | OK | S100a9 | ↓ | OK | ↓ | OK | ↓ | OK | |||||
| Egr1 | ↑ | OK | ↑ | OK | ↑ | OK | S100g | OK | OK | OK | ||||||||
| Egr2 | ↑ | OK | ↑ | OK | ↑ | OK | Scg2 | ↓ | OK | ↓ | OK | ↓ | OK | |||||
| Eno2 | ↑ | OK | ↑ | OK | OK | Sgk1 | OK | ↑ | OK | ↑ | OK | |||||||
| Fgf6 | B | B | B | Slc18a1 | ↓ | OK | ↓ | OK | ↓ | OK | ||||||||
| Fos | OK | ↑ | OK | OK | Sod2 | ↑ | OK | ↑ | OK | ↑ | OK | |||||||
| Fosb | OK | ↑ | OK | ↑ | OK | Srf | OK | ↑ | OK | ↑ | OK | |||||||
| Gcg | ↓ | OK | ↓ | OK | ↓ | OK | Sst | ↓ | OK | ↓ | OK | ↓ | OK | |||||
| Gem | OK | ↑ | OK | OK | Sstr2 | B | OK | OK | ||||||||||
| Hk2 | OK | OK | OK | Stat3 | ↑ | OK | ↑ | OK | ↑ | OK | ||||||||
| Hspa4 | OK | OK | OK | Tacr1 | ↓ | OK | ↓ | OK | ↑ | A | ||||||||
| Hspa5 | ↑ | OK | ↑ | OK | ↑ | OK | Tgfb3 | OK | ↑ | OK | ↑ | OK | ||||||
| Il2 | ↓ | OK | ↓ | OK | ↓ | OK | Th | ↑ | OK | ↑ | OK | ↑ | A | |||||
| Il6 | ↑ | A | ↑ | A | OK | Thbs1 | ↑ | OK | ↑ | OK | ↑ | OK | ||||||
| Inhba | ↑ | OK | ↑ | OK | ↑ | OK | Tnf | ↓ | OK | ↓ | OK | ↓ | OK | |||||
| Junb | ↑ | OK | ↑ | OK | OK | Vcl | OK | OK | OK | |||||||||
| Jund | ↑ | OK | OK | ↓ | OK | Vip | ↓ | OK | ↓ | OK | ↓ | OK | ||||||