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. 2023 Feb 20;18(14):1165–1177. doi: 10.4244/EIJ-D-22-00644

Figure 6. Collagen structure analysis based on SHG microscopy imaging of THV leaflets.

Figure 6

Summary of the entropy analysis calculated from SHG images. A higher degree of entropy indicates a higher degree of collagen fibre disorganisation. A) Entropy according to BVF timing in the ACn. B) The same analysis but looking at the ventricular and aortic sides separately. C) Entropy according to BVF timing in the S3. D) The same analysis but looking at the ventricular and aortic sides separately. ACn: ACURATE neo; a.u.: arbitrary units; BVF: bioprosthetic valve fracture; S3: SAPIEN 3; SHG: second-harmonic generation; THV: transcatheter heart valve