TABLE 1. Participants’ characteristics stratified for excessive alcohol and MAFLD status.
MAFLD−/Alc− n = 7610 | MAFLD+/Alc− n = 3399 | MAFLD−/Alc+ n = 1146 | MAFLD+/Alc+ n = 501 | |
---|---|---|---|---|
Demographics | ||||
Age (years) | 38.7 [28.5, 55.4] | 49.9 [37.4, 63.3] | 36.9 [27.4, 49.8] | 44.8 [34.7, 58.8] |
Male | 3226 (42.4) | 1553 (45.7) | 706 (61.6) | 360 (71.9) |
Race | ||||
Mexican‐American | 2024 (26.6) | 1278 (37.6) | 276 (24.1) | 208 (41.5) |
Non‐Hispanic Black | 2383 (31.3) | 779 (22.9) | 364 (31.8) | 95 (19.0) |
Non‐Hispanic White | 2871 (37.7) | 1215 (35.7) | 482 (42.1) | 179 (35.7) |
Other | 332 (4.4) | 127 (3.7) | 24 (2.1) | 19 (3.8) |
College | 2538 (33.6) | 792 (23.4) | 367 (32.3) | 121 (24.3) |
Current smoking | 2100 (27.6) | 699 (20.6) | 654 (57.1) | 221 (44.1) |
MAFLD criteria | ||||
BMI ≥ 25 | 3932 (51.7) | 3039 (89.4) | 491 (42.8) | 438 (87.4) |
Diabetes | 648 (8.8) | 969 (29.1) | 69 (6.2) | 101 (20.4) |
Metabolic dysfunction | 3624 (47.6) | 3040 (89.4) | 462 (40.3) | 435 (86.8) |
Biochemistry | ||||
AST (U/L) | 18 [15, 22] | 20 [17, 26] | 20 [17, 25] | 24 [19, 33] |
ALT (U/L) | 13 [10, 18] | 17 [12, 26] | 14 [10, 19] | 21 [15, 36] |
HDL‐C (mmol/L) | 1.35 (0.37) | 1.16 (0.34) | 1.52 (0.49) | 1.31 (0.45) |
Triglycerides (mmol/L) | 1.13 [0.81, 1.62] | 1.79 [1.23, 2.59] | 1.11 [0.80, 1.65] | 1.80 [1.18, 2.79] |
HbA1c (%) | 5.4 (0.9) | 6.0 (1.5) | 5.2 (0.6) | 5.5 (1.0) |
Note: Data are presented as mean (SD), median [P25‐P75], or n and percentage.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; P25‐P75, 25th–75th percentile.