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. 2021 Nov 29;45(1):140. doi: 10.1016/j.htct.2021.09.014

Palatal superficial mucoceles associated with chronic graft-versus-host disease

Bilal Al Masri 1, Linda M Perry 1, Eric T Stoopler 1,
PMCID: PMC9938450  PMID: 34872883

A 23-year-old woman with history of acute myelogenous leukemia post Busulfan and Cytoxan conditioned 10/10 sibling donor peripheral blood stem cell transplant day +336 post-transplant and chronic graft-versus-host disease (cGVHD) with mild hepatic and cutaneous involvement complained of symptomatic palatal lesions consistent with superficial mucoceles (Figure 1). Following unsuccessful treatment with topical corticosteroids, symptomatic improvement was achieved with dissolved budesonide powder in water rinses three times daily.

Figure 1.

Figure 1

Multiple translucent vesicles with inflammation on soft palate consistent with superficial mucoceles.

Symptomatic superficial mucoceles are an uncommon manifestation of oral cGVHD and appear as translucent vesicles on the palate or labial mucosae. 1,2 Topical or injectable corticosteroids are commonly used for management.1,2

Conflicts of interest

The authors declare no conflicts of interest.

References

  • 1.Balasubramaniam R, Alawi F, DeRossi S. Superficial mucoceles in chronic graft-versus-host disease: a case report and review of the literature. Gen Dent. 2009;57(1):82–88. [PubMed] [Google Scholar]
  • 2.Deutsch A, McLellan BN. Topical tacrolimus for refractory superficial mucoceles in a patient with chronic graft versus host disease. JAAD Case Rep. 2020;6(5):426–427. doi: 10.1016/j.jdcr.2020.02.041. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Hematology, Transfusion and Cell Therapy are provided here courtesy of Sociedade Brasileira de Hematologia e Hemoterapia

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