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. 2023 Feb 21;110:112008. doi: 10.1016/j.nut.2023.112008

Table 3.

Association between vitamin D and sleep quality during the COVID-19 pandemic

Total
Exposure to sunlight
Unadjusted
Adjusted *
Sufficient (64.9%)
Insufficient (35.1%)
OR 95% CI OR 95% CI OR 95% CI OR 95% CI
Vitamin D
 Sufficiency 1.00 1.00 1.00 1.00
 Deficiency 1.17 0.68–2.02 1.08 0.63–1.82 0.85 0.43–1.72 2.02 1.10–3.71
 AIC 2362.622 2280.924 1261.312 949.934
Continuous value
ng/mL 0.99 0.98–1.01 1.00 0.98–1.03 1.02 0.99–1.06 0.96 0.92–0.99
AIC 2359.420 2190.415 1257.890 950.658

AIC, Akaike information criterion.

The outcome variable evaluated was poor sleep quality (Pittsburgh Sleep Quality Index ≥5); vitamin D concentrations were classified according to the Institute of Medicine as deficient when 25(OH)D < 20 ng/mL and sufficient when 25(OH)D ≥ 20 ng/mL

Directed acyclic graph (DAG) was used to support the theoretical model for the adjusted analysis. Adjusted analysis was by the following minimum and sufficient set of variables: age (continuous variable), sex (male or female), skin color (white, black, brown, or other), education (0 to 8 y, 9 to 11 y, or >12 y), employment status (not working or actively working), alcohol consumption (no or yes), body mass index (continuous variable; kg/m2), presence of chronic diseases (no or yes), mental health (presence of anxiety or depression symptoms), physical activity (physically active or physically inactive), exposure to sunlight (continuous variable, min/d), and vitamin D supplementation (no or yes).

Analysis stratified by solar exposure and the minimum and sufficient set of variables is presented.