This Research Topic is devoted to innovations in Analytical Chemistry. Three articles and one mini review were published.
Mass spectrometry is the basic technique for two papers. Matrix-assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI-MSI) coupled with other imaging modalities in multimodal approaches is reviewed for in vivo and in vitro biological applications. (Tuck et al.) Differential cell-surface N-glycosylation of ovarian cancer SKOVS cells were analyzed by HPLC-MS/MS on the enriched and labeled N-glycopeptides and compared to non-cancerous ovarian epithelial IOSE80 cell lines. This study provides important N-glycoprotein biomarker candidates for future studies (Zhou et al.).
Isothermal reverse transcription recombinase polymerase amplification (RT-RPA) is a simple, sensitive and cheap molecular diagnostic method. RT-RPA is here combined with a magnetic field-enhanced agglutination (MFEA) assay for the detection of the dengue virus (DENV). A rapid, sensitive and specific test is then obtained (Leon et al.).
Author contributions
CB, Editor; NJ-R, Editor; GM, Editor; GV, Editor.
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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