Table 2.
Lateralization performance using T1, T2, and CESTR from the hippocampus (A) or amygdala (B) alone.
| A | Hippocampus |
|
|---|---|---|
| M1 | M2 | |
| Index | AUC (95% CI) | AUC (95% CI) |
| T1 | 0.78 (0.62, 0.93), p < 0.01 | 0.78 (0.63, 0.94), p < 0.01 |
| T2 | 0.78 (0.63, 0.93), p < 0.01 | 0.78 (0.63, 0.93), p < 0.01 |
| CESTR | 0.82 (0.68, 0.95), p < 0.01 | 0.81 (0.67, 0.94), p < 0.01 |
| B | Amygdala |
|
|---|---|---|
| M1 | M2 | |
| Index | AUC (95% CI) | AUC (95% CI) |
| T1 | 0.70 (0.53, 0.87), p = 0.04 | 0.69 (0.52, 0.86), p = 0.05 |
| T2 | 0.72 (0.56, 0.89), p = 0.02 | 0.72 (0.56, 0.89), p = 0.02 |
| CESTR | 0.73 (0.57, 0.89), p = 0.02 | 0.74 (0.59, 0.90), p = 0.01 |
The CESTR value was the mean within 2.25–3.25 ppm as in Table 1. Both difference (M1) and ratiometric (M2) asymmetry measurements between the two hemispheres were evaluated for each index. The AUC values of CESTR were the highest in both hippocampus and amygdala. For every index, the AUC from the hippocampus was higher than that from the amygdala. Two subjects of the total 40 patients were excluded due to the small size of the hippocampus or amygdala (<8 voxels).