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. 2023 Jan 31;13(2):266. doi: 10.3390/biom13020266

Figure 3.

Figure 3

Algorithm summarizing mechanisms linking high miR193a, podocyte detachment, and PEC activation in classical FSGS (blue), CG (green), and CrescGN (red). PEC—parietal epithelial cell; PD—podocyte; WT1—Wilms’ tumor protein 1; BS—Bowman’s space; CL—capillary lumen; GBM—glomerular basement membrane; FSGS—focal segmental glomerulosclerosis; CG—collapsing glomerulopathy; CrescGN—crescentic glomerulonephritis; mTOR—mammalian target of rapamycin; Notch1—Neurogenic locus notch homolog protein 1; GR—glucocorticoid receptor.