Fig. 6.

Anti-inflammatory activity of four compounds in macrophages. The level of NO (A), IL-6 (B), TNF-α (C) was determined using an assay kit. The mRNA expressions of IL-1β (D), iNOS (E) and MyD88 (F) were measured by RT-qPCR. Values are presented as the x ± s, n = 3. Analyses were performed using a one-way ANOVA. ####p < 0.001 vs. the con group; *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 vs. the LPS group. Compounds 9, 10, 17, and 21 were identified as eriodictyol-7-O-glucoside, luteoloside, apigenin 7-O-glucoside, and diosmetin 7-O-glucoside, respectively.