Heterogeneity of the HVRs in the S1 subunit of the Kenyan A374/17 (in red color) compared to other IBVs. Dots and dashes in the alignments indicate identical and missing (or gaps in alignment of) amino acid residues, respectively. Amino acid residue positions are numbered in reference to the consensus sequence. UV indicates a unique variant. The amino acid residues highlighted with asterisks in shaded boxes (“*”; i.e., N38, H43, S56, P63, I66, and T69) are reportedly critical for attachment of the GI-1 prototype strain AY851295/M41 (in blue color) to chicken respiratory tract tissues [48]. The classification is based on Valastro et al. [19].