Table 1.
Descriptive baseline characteristics by Mg status at admission: the COMEPA study.
| Parameter | Serum Mg > 1.96 mg/dL (n = 186) | Serum Mg ≤ 1.96 mg/dL (n = 74) | p-Value |
|---|---|---|---|
| Demographics | |||
| Age (years) | 63.9 (15.7) | 69.1 (13.4) | 0.01 |
| Males (%) | 51.6 | 59.5 | 0.27 |
| Current smoking (%) | 12.1 | 9.8 | 0.80 |
| Alcohol abuse (%) | 6.1 | 10.4 | 0.34 |
| Laboratory parameters (1–4 days) | |||
| Creatinine clearance (mL/min) | 91.7 (32.0) | 87.8 (45.5) | 0.50 |
| Hemoglobin (g/dL) | 13.1 (1.9) | 11.6 (2.2) | <0.0001 |
| White blood cells (units/μL) | 7940 (4214) | 7212 (3264) | 0.14 |
| CRP (mg/mL) | 51.2 (48.9) | 60.0 (64.6) | 0.31 |
| IL-6 (pg/mL) | 36.4 (71.0) | 59.8 (136.1) | 0.19 |
| Procalcitonin (ng/mL) | 0.82 (6.84) | 0.43 (1.26) | 0.68 |
| PaO2/FiO2 ratio | 324 (104) | 344 (142) | 0.29 |
| Serum 25OHD (ng/mL) | 24 (19) | 23 (14) | 0.78 |
| AST (U/L) | 31 (25) | 26 (15) | 0.21 |
| ALT (U/L) | 37 (46) | 25 (19) | 0.003 |
| Fasting plasma glucose (mg/dL) | 131 (62) | 141 (71) | 0.29 |
| Na (mmol/L) | 139 (4) | 139 (4) | 0.88 |
| Ca++ (mmol/L) | 8.94 (0.93) | 8.95 (0.63) | 0.99 |
| K (mg/dL) | 4.38 (0.67) | 4.43 (0.58) | 0.10 |
| Albumin (g/L) | 3.57 (0.51) | 3.36 (0.47) | 0.002 |
| Clinical data | |||
| Any COVID-19 symptomatology (%) | 82.3 | 63.0 | 0.002 |
| CIRS-SI | 1.41 (1.42) | 2.74 (1.81) | <0.0001 |
AST: aspartate aminotransferase; ALT; alanine transaminase; Ca: calcium; CIRS-SI: Cumulative Illness Rating Scale-Severity Index; COMEPA: COVID-19 Palermo; COVID-19: coronavirus-19 disease; CRP: C-reactive protein; IL-6: interleukin-6; K: potassium; Na: sodium; PaO2/FiO2: partial pressure of oxygen/fraction of inspired oxygen; 25OHD: 25 hydroxyvitamin D.