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. 2023 Feb 2;15(2):498. doi: 10.3390/pharmaceutics15020498

Table 3.

Kinetic parameters for the F1FO-ATPase inhibition by Pzs. IC50 and Ki values were graphically obtained from the Pzs’ titration curve and Cornish-Bowden plots of Figure 3 and Figure 4, respectively.

Entry a Compound IC50 (mM) Ki (mM)
1 6a 0.25 ± 0.01 0.21 ± 0.03
2 6h 1.62 ± 0.85 1.27 ± 0.25
3 6o 0.21 ± 0.15 1.86 ± 0.33

a Data are the mean ± SD of three independent experiments carried out on different mitochondrial preparations.