Table 3.

Examples of clinically important and well defined weak D types^*

Weak D type	Position involved	Substitution	Intracellular/transmembranous
1	270	Val to Gly9	transmembranous
2	385	Gly to Ala9	transmembranous
3	3	Ser to Cys9	intracellular
4.0	201	Thr to Arg9	transmembranous
	223	Phe to Val9	transmembranous
4.1	16	Trp to Cys50	transmembranous
	201	Thr to Arg	transmembranous
	223	Phe to Val	transmembranous
4.2†	201	Thr to Arg50	transmembranous
	223	Phe to Val	transmembranous
	342	Ile to Thr	transmembranous
5	149	Ala to Asp9	transmembranous
11	295	Met to Ile9	transmembranous
15	282	Gly to Asp9	transmembranous
20	417	Phe to Ser88	intracellular

^*A regularly updated list can be found at the RhesusBase: http://www.uniulm.de/~wflegel/Rh/.

^†The protein sequence of weak D type 4.2 is identical to the partial D DAR.⁵⁹