Abstract
How to cite this article: Rasmussen M, Sunnerhagen T. Get the Species Right: Aerococcus viridans is Likely not Responsible. Indian J Crit Care Med 2022;26(10):1158.
Keywords: Aerococcus, Bacteremia, Vitek2
We read with interest the article “Aerococcus viridans bacteremia: A rare case report from India” published in your journal.1 While we find new information on aerococci and aerococcal infection is much called for, such information needs to be correct. The authors of this report claim that the infection described was caused by A. viridans but they use a method for species identification, Vitek2, which is known to misidentify Aerococcus sanguinicola as A. viridans.1,2 Furthermore, A. sanguinicola is a more common cause of severe aerococcal infections3,4 and it is likely that the most reported cases of A. viridans infections, including the one by Varshini et al., actually represents infections with another bacterium, with A. sanguinicola being likely 2,4 Varshini et al. also claim that the isolated bacteria induced β-hemolysis on blood agar plates which is a very atypical feature for an Aerococcus. We, therefore, believe it very likely that the case report describes an infection, not with A. viridans, but with a yet undetermined bacterial species. A correct species determination of bacteria is a prerequisite in scientific reports as errors in species determination risks to add to confusion and not to knowledge. Both matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF MS) and methods based on 16S rDNA sequencing could have been used to determine species of the bacterium in this case.5
Orcid
Magnus Rasmussen https://orcid.org/0000-0003-1588-5473
Torgny Sunnerhagen https://orcid.org/0000-0002-9240-2378
Footnotes
Source of support: Nil
Conflict of interest: None
References
- 1.Varshini K, Ganesan V, Charles J. Aerococcus viridans bacteremia: A rare case report from India. Indian J Crit Care Med. 2022;26(1):127–128. doi: 10.5005/jp-journals-10071-24072. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Rasmussen M. Aerococcus: An increasingly acknowledged human pathogen. Clin Microbiol Infect. 2016;22(1):22–27. doi: 10.1016/j.cmi.2015.09.026. [DOI] [PubMed] [Google Scholar]
- 3.Senneby E, Göransson L, Weiber S, Rasmussen M. A population-based study of aerococcal bacteraemia in the MALDI-TOF MS-era. Eur J Clin Microbiol Infect Dis. 2016;35(5):755–762. doi: 10.1007/s10096-016-2594-z. [DOI] [PubMed] [Google Scholar]
- 4.Berge A, Kronberg K, Sunnerhagen T, Nilson BHK, Giske CG, Rasmussen M. Risk for Endocarditis in bacteremia with Streptococcus-like bacteria: A retrospective population-based cohort study. Open Forum Infect Dis. 2019;6(10):ofz437. doi: 10.1093/ofid/ofz437. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Rasmussen M. Aerococci and aerococcal infections. J Infect. 2013;66(6):467–474. doi: 10.1016/j.jinf.2012.12.006. [DOI] [PubMed] [Google Scholar]
