Calcineurin Controls Drug Tolerance, Hyphal Growth, and Virulence in Candida dubliniensis -- Chen et al. 10 (6): 803 Data Supplement

Calcineurin Controls Drug Tolerance, Hyphal Growth, and Virulence in Candida dubliniensis
Eukaryotic Cell Chen et al. 10: 803

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Supplemental file 1 - PCR primers used in the study (Table S1); C. dubliniensis CNA1, CNB1, and CRZ1 genes were disrupted with the SAT1 flipper (Fig. S1); complementation by CRZ1 rescues crz1/crz1 mutants in various stresses (Fig. S2); C. dubliniensis calcineurin is dispensable for growth at elevated temperature (Fig. S3); calcineurin controls increased tolerance to new-generation azoles in C. dubliniensis (Fig. S4); crz1/crz1 mutants are hypersensitive to CaCl₂ at elevated temperature in C. dubliniensis and C. albicans (Fig. S5); calcineurin is required for germ tube formation in C. dubliniensis but not in C. albicans (Fig. S6); C. dubliniensis is as virulent as C. albicans in a heterologous insect model (Fig. S7); C. dubliniensis exhibits less hyphal growth and damage to oral epithelial cells than C. albicans (Fig. S8).
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