Phosphorylation by p38 Mitogen-Activated Protein Kinase Promotes Estrogen Receptor α Turnover and Functional Activity via the SCF^Skp2 Proteasomal Complex

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 - Fig. S1 (Skp2 regulation of ERα levels and stability), S2 (Cul-7 and Rbx-1 in Skp2-mediated proteasomal degradation of ERα), S3 (ERα phosphorylation and ubiquitination by Skp2), S4 (ERα knockdown, Skp2 and phospho-p38MAPK recruitment, and Skp2 and p38MAPK in S-phase entry), S5 (ERα loss and Skp2 and p38MAPK levels), S6 (Skp2 mutants and ERα target gene expression or cell proliferation), S7 (ERα mRNA after knockdown of Skp2 or p38MAPK inhibition), and S8 (Skp2 and p38MAPK knockdown and pS2 and GREB1 mRNA expression)
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