Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF-κB Activation through TBK1

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Fig. S1 (STING ligand-mediated signaling response in MEFs.)

  Fig. S2 (HSV-1-mediated signaling response in MEFs.)

  Fig. S3 (TBK1 is not involved in dsDNA-mediated MAPK activation.)

  Fig. S4 (IKKi/IKKε and NIK are not involved in the STING-dependent, dsDNA-mediated signaling response in MEFs.)

  PDF, 2.2M