The E3 Ligase CHIP Mediates Ubiquitination and Degradation of Mixed-Lineage Kinase 3

Supplemental material

Files in this Data Supplement:

• Supplemental file 1 -

  Legends to Fig. S1 to S4

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• Supplemental file 2 -

  Fig. S1 (MLK3 levels in extracts of GA-treated cells)

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• Supplemental file 3 -

  Fig. S2 (CHIP in GA-induced degradation of MLK3)

  PDF, 370K

• Supplemental file 4 -

  Fig. S3 (MLK3 in sorbitol-dependent activation of JNK)

  PDF, 267K

• Supplemental file 5 -

  Fig. S4 (TNFα and endogenous MLK3 level)

  PDF, 157K