Optimal Cutoff and Accuracy of an IgM Enzyme-Linked Immunosorbent Assay for Diagnosis of Acute Scrub Typhus in Northern Thailand: an Alternative Reference Method to the IgM Immunofluorescence Assay

Supplemental material

• Supplemental file 1 -

  Table S1 (IgM ELISA OD for admission-, convalescent-, and discharge-phase samples at a 1:400 sample dilution for 29 patients with blood culture positive for O. tsutsugamushi, positive results for a combination of PCR assays, or the presence of an eschar)

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• Supplemental file 2 -

  Fig. S1 (Unbiased ROC curves obtained using Bayesian LCMs for all possible cutoff ODs for IgM ELISA at sample dilutions from 1:100 to 1:102,400 for admission-phase samples alone)

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• Supplemental file 3 -

  Fig. S2 (Unbiased ROC curves obtained using Bayesian LCMs for all possible cutoff ODs for IgM ELISA at sample dilutions from 1:100 to 1:102,400 for paired convalescent-phase samples)

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• Supplemental file 4 -

  Text S1 (Data set for Bayesian latent class models)

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• Supplemental file 5 -

  Text S2 (WinBUGS models)

  PDF, 77K