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Table 7. Demographic and performance data for subjects in the episodic memory study
|
|
A/A genotype group |
A/G and G/G genotype group |
F value |
P value |
|
n |
32 |
32 |
|
|
|
Age |
28.9(±8.0) |
28.3(±8.0) |
|
n.s. |
|
Gender |
14 Female |
14 Female |
|
n.s. |
|
Handedness* |
.64(±.66) |
.77 (±.44) |
|
n.s. |
|
Education, yrs |
16.2(±2.2) |
17.2(±3.5) |
|
n.s. |
|
Subject SES |
49.4(±11.7) |
48.4(±17.0) |
|
n.s. |
|
IQ |
103.8(±9.7) |
105.6(±9.5) |
|
n.s. |
|
WRAT |
109.6(±9.2) |
105.1(±11.0) |
3.02 |
0.08 |
|
encoding % Correct |
93.0(±7.0) |
93.5(±4.1) |
|
n.s. |
|
encoding RT (ms) |
1319.6 (±175.0) |
1354.3 (±176.0) |
|
n.s. |
|
retrieval % Correct |
87.2 (±12.6) |
84.0 (±13.4) |
|
n.s. |
|
retrieval RT (ms) |
1506.2 (±191.5) |
1557.3 (±147.8) |
|
n.s. |
Demographic and performance data (± SD) for healthy control subjects in the fMRI episodic memory study. Stimuli were presented in four encoding blocks followed by four retrieval blocks in an interleaved design with a passive rest condition. During encoding blocks, subjects viewed images and determined whether they were "indoor" or "outdoor" scenes. During retrieval blocks, subjects images and determined if they were "new" or "old." In each retrieval block, half the scenes were "old" and half were "new." During interleaved rest blocks, subjects fixated on a central cross-hair. Accuracy and reaction time were collected.
Data collected during the episodic memory task were analyzed in two steps, similar to data for the N back task. Because we did not have a priori hypotheses regarding the activity of brain regions outside of the hippocampal formation, we used a statistical threshold of P < 0.05, corrected for multiple comparisons across all supra-threshold voxels, for these whole-brain comparisons. Genotype groups are well matched on all variables. RT, reaction time; WRAT, Wide Range Achievement Test.
*Edinburg Handedness Score