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Table 3. Summary of non-small cell lung cancer (NSCLC) tumors analyzed for epidermal growth factor receptor (EGFR) mutations in this study
|
Characteristics of NSCLC tumors |
Tissue type |
No. of tumors evaluated |
No. of tumors with EGFR mutation |
% positive for EGFR mutation |
p value(Fisher’s exact) |
|
Gefitinib-sensitive |
Paraffin |
10 |
7 |
70 |
0.004 |
|
Gefitinib-refractory |
Paraffin |
8 |
0 |
0 |
|
|
Erlotinib-sensitive |
Paraffin |
7 |
5 |
71 |
0.003 |
|
Erlotinib-refractory |
Paraffin |
10 |
0 |
0 |
|
|
Untreated from "never smoker" with adenocarcinoma |
Frozen |
15 |
7 |
47 |
0.0001 |
|
Untreated from former/current smokers with NSCLC |
Frozen |
81 |
4 |
5 |
|
|
Total untreated |
Frozen |
96 |
11 |
12 |
Not applicable |