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Burgess et al. 10.1073/pnas.0305789101.

Supporting Information

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Supporting Text
Supporting Figure 6
Supporting Figure 7
Supporting Table 3
Supporting Table 4




Supporting Figure 6

Fig. 6. Chicken CD30 promoter sequence. Sequences complementary to PCR primer sequences used for amplifying region and used for luciferase assay are in italics. Transcription factor binding sites predicted by MATINSPECTOR (core and matrix similarity values of 1.0 and ³ 0.9, respectively) and ALIBABA-2 are underlined; adjacent sites demarcated by vertical lines. Bold ATG identifies the start of the ORF.





Supporting Figure 7

Fig. 7. The alignment used to determine the similarities and replacement/substitution (r/s) ratios when comparing human and mouse exons. In the alignment, nucleotides identical to those in human exons 3 and 4 (H3 and H4) are shown in mouse exons 3 and 4 (M3 and M4) or human exons 7 and 8 (H7 and H8) by dashes; r indicates differences causing amino acid replacements; s indicates differences that do not. These are shown above the sequences for the comparison of human exons 3 and 4 to human exons 7 and 8, and below for comparison of human and mouse exons 3 and 4. The extra line below refers to the comparison of mouse exons 3 and 4 with human exons 7 and 8. The underlined sequence is the region encoding human TNFR repeat 2.