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Guo et al. 10.1073/pnas.0405878101. |
Supporting Information
Files in this Data Supplement:
Supporting Figure 6
Supporting Table 1
Supporting Figure 6
Fig. 6. Microarray analysis of DT-40 cells with WT Btk or Btk Y617E mutant. (A) Total number of differentially expressed genes. (I) Ninety-six genes differentially expressed between WT cells (0 h) and WT cells (2 h). (II) Thirty-two genes differentially expressed between WT cells (2 h) and Y617E cells (2 h). (III) Seven genes differentially expressed in both comparisons. (B) Selected differentially expressed genes.
Supporting Table 1
Table 1. Full list of genes from the chicken cDNA chips. Clone ID and accession numbers are followed by annotation. The adjusted fold change from each sample is listed, and the P values were calculated by using a Bayesian approach with the program CYBERT. Highlighted genes have an adjusted P value >0.01, as calculated by using the Benjamini and Hochberg method, meaning that they have an estimated false-positive rate >1%. Blank spaces indicate flagged data points and were not used in statistical calculations. WT2, WT at 2-h stimulation; WT0, WT no stimulation; 6ITE2, Y617TE mutant at 2-h stimulation. -1 and -2, duplicate samples. All WT2 vs. WT0 and WT0 vs. WT2 ratios are listed as WT(2 h) / WT(0 h), and all Y617E2 vs. WT2 and WT2 vs. Y617E2 ratios are listed as Y617E(2 h) / WT(2 h).
