Fig. S1. Gating strategy for PD-1 and CXCR5 expression and BCL6 expression in activated CD4 T cells. Fig. S2. Neutralization of IL-6 does not affect the generation of Tfh lineage cells. Fig. S3. MyD88 expression in CD4 T cells during antigen-specific differentiation. Fig. S4. Intradermal infection of mice by Borrelia burgdorferi leads to measurable and sustained Tfh and GC responses in the spleen that fail to confer protection in the absence of MyD88 in T cells. Fig. S5. Functional characterization of CD2-MyD88 Tg mice on a MyD88-deficient background.
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