Fig. 3. Cerebellar and brain-wide networks involved in eating behaviours.

a Cerebellar regions shown to be involved in homeostatic (grey), motor (blue), reward (yellow) and affective (purple) aspects of eating. Animal studies are depicted on an outline of the rat cerebellum on the left, and human studies are shown on the right. The numbers correspond to the studies detailed in Table 1. b The cerebellum has connections with brain regions contributing to homeostatic (grey), motor (blue), reward (yellow) and affective (purple) domains of eating behaviours, depicted in a (i) rat and (ii) human brain outline. Connections may be direct or indirect; the latter is the case for cerebello-thalamo-cortical pathways. We propose that the cerebellum has a unifying role via prediction signals which contributes to each of these components. Note that this diagram is not comprehensive, but represents key structures discussed in this review. PFC, prefrontal cortex; VTA, ventral tegmental area; RN, red nucleus; PAG, periaqueductal grey; PBN, parabrachial nucleus; NTS. nucleus tractus solitaries