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. Author manuscript; available in PMC: 2017 Jan 25.
Published in final edited form as: Hypertension. 2016 Dec 27;69(2):275–285. doi: 10.1161/HYPERTENSIONAHA.115.07031

Figure 2. Functional consequences of selective ETB deletion from smooth muscle (SM).

Figure 2

(A) Sarafotoxin s6C (S6c)-induced contraction of isolated trachea was abolished by ETB receptor antagonism (A192621; 100nM) but only reduced by selective SMETB deletion (residual contraction was blocked by A192621). Columns are mean ± s.e.mean (n=4). *P<0.02; **P<0.005. (B) S6c-induced contraction in murine mesenteric veins was abolished by SMETB deletion. Symbols represent mean ± s.e.mean (n=4). *P<0.05, **P<0.01.