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. Author manuscript; available in PMC: 2019 Jul 18.
Published in final edited form as: Circulation. 2019 May 14;139(20):2358–2371. doi: 10.1161/CIRCULATIONAHA.118.039329

Fig 5.

Fig 5

Effects of altered buffer power. A. Abolition of centripetal propagation of the Ca2+ transient by rapid atrial pacing (RAP). Upper traces are linescan images. Lower records show [Ca2+]i measured at surface of cell (black) and in centre (green). Left hand records from control and right hand after rapid stimulation. Reproduced from 71. B. Relaxation of contraction in isolated rat myocytes. Records show control (euthyroid), hypothyroid, and hypothyroid with parvalbumin expressed by gene transfer. Reproduced from 72. C. Left, comparison of the effects of the I79N mutation of troponin T with that of the Ca2+ sensitizing agent EMD 57033 on the relationship between pCa and force. Right, effects of EMD 57033 on occurrence of ventricular tachycardia (VT). Reproduced from 73.