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. Author manuscript; available in PMC: 2020 Jun 29.
Published in final edited form as: Glia. 2020 Feb 10;68(7):1479–1494. doi: 10.1002/glia.23796

FIGURE 1.

FIGURE 1

Microgliosis occurs in the MBH throughout PDAC cachexia. (a) Representative confocal microscopy images of Iba-1 immunoreactivity within the MBH, hippocampus, and cortex from either a sham, 7 dpi, or 10 dpi mouse brain. Scale bar = 100 µm. Top left inset = arcuate nucleus microglia within left box. Top right inset = median eminence microglia within right box. Inset scale bars = 10 µm. B-E) Analysis of microglia number (left) or percent area Iba-1+ (right) in the arcuate nucleus, median eminence, hippocampus, or cortex. n.s. = not significant, ***p < .001, **p < .01, *p < .05 compared to sham in one-way ANOVA analysis