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. Author manuscript; available in PMC: 2021 Dec 8.
Published in final edited form as: ChemMedChem. 2021 Oct 12;17(1):e202100455. doi: 10.1002/cmdc.202100455

Table 2.

IC50 values of identified cysteine protease inhibitors against SC2PLpro

Name IC50 (µM)
NSC18058 *
Leupeptin *
HY-17541A *
HY-17541 *
PMSF *
EP1013 *
S130 35.0 ± 1.4
Petesicatib *
Tauroursodeoxycholate *
Emricasan *
N-Ethylmaleimide *
CA-074 *
CA-074 methyl ester *
Z-VAD(OMe)-FMK *
Aloxistatin *
Q-VD-OPh *
H-Arg-4MβNA *
LY 3000328 *
BOC-D-FMK *
Z-DEVD-FMK *
E-64 *
Balicatib *
Odanacatib *
Belnacasan *
Calpetin *
E 64c *
3-Epiursolic Acid *
MDL-28170 *
Chelidonic acid *
MG-101 *
Z-VAD-FMK *
OT-82 *
IKarisoside A *
Wedelolactone *
Phenoxodiol *
2-Cyanopyrimidine *
Z-WEHD-FMK *
*

: not determined.